STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (461 aa)    
Predicted Functional Partners:
KXB81946.1
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.995
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
 
 0.989
KXB80385.1
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.944
KXB82129.1
KEGG: pmz:HMPREF0659_A6909 3.4e-128 fabD; [acyl-carrier-protein] S-malonyltransferase K00645; Psort location: Cytoplasmic, score: 9.26.
 
 
 0.938
KXB78804.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.923
KXB78088.1
Beta-ketoacyl synthase protein; KEGG: wvi:Weevi_1565 1.2e-95 beta-ketoacyl-acyl-carrier-protein synthase II; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.921
KXB78086.1
KEGG: tfo:BFO_1314 1.5e-72 Beta-ketoacyl synthase, C-terminal domain-containing protein; K00647 3-oxoacyl-[acyl-carrier-protein] synthase I; Psort location: CytoplasmicMembrane, score: 7.88; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.908
KXB78079.1
KEGG: pdn:HMPREF9137_2056 5.3e-194 fabB; beta-ketoacyl-acyl-carrier-protein synthase I K00647; Psort location: Cytoplasmic, score: 9.26; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.904
KXB78077.1
Putative 3-oxoacyl-[acyl-carrier-protein] reductase; KEGG: pdn:HMPREF9137_2055 9.6e-92 short chain dehydrogenase/reductase family oxidoreductase; K00059 3-oxoacyl-[acyl-carrier protein] reductase; Psort location: Cytoplasmic, score: 9.26.
 
 0.882
KXB78084.1
Hypothetical protein; KEGG: zga:zobellia_2073 1.3e-18 fabZ2; (3R)-hydroxymyristoyl-ACP dehydratase; Psort location: Cytoplasmic, score: 8.96.
   
 0.867
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.