STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB81387.1Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (347 aa)    
Predicted Functional Partners:
KXB81388.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
KXB79141.1
Putative ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.971
cmk
Cytidylate kinase; KEGG: pmz:HMPREF0659_A7170 4.4e-87 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 9.97.
    
 0.723
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.721
KXB79506.1
Pyruvate kinase; KEGG: pdn:HMPREF9137_0096 1.9e-189 pyk; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 9.97.
     
 0.686
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.664
KXB80105.1
KEGG: pmz:HMPREF0659_A5634 0. nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.536
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
       0.501
KXB78229.1
Hypothetical protein; KEGG: pdn:HMPREF9137_0362 5.6e-135 hypothetical protein; K00208 enoyl-[acyl-carrier protein] reductase I; Psort location: CytoplasmicMembrane, score: 9.82.
     
 0.496
KXB77325.1
KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.490
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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