| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB75702.1 | metK | HMPREF1860_01743 | HMPREF1860_00337 | NAD dependent epimerase/dehydratase family protein; KEGG: sgo:SGO_2016 1.7e-71 nucleotide sugar dehydratase K01710; Psort location: Cytoplasmic, score: 9.26. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.806 |
| KXB78055.1 | metK | HMPREF1860_01097 | HMPREF1860_00337 | KEGG: pdn:HMPREF9137_0844 1.2e-134 NAD dependent epimerase/dehydratase family protein; Psort location: Cytoplasmic, score: 8.96. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.806 |
| KXB80113.1 | metK | HMPREF1860_00399 | HMPREF1860_00337 | KEGG: abu:Abu_1481 3.9e-72 DNA (cytosine-5-)-methyltransferase K00558; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.843 |
| KXB80393.1 | metK | HMPREF1860_00309 | HMPREF1860_00337 | NAD dependent epimerase/dehydratase family protein; KEGG: bfs:BF4355 1.5e-102 UDP-glucose 4-epimerase K01784; Psort location: Cytoplasmic, score: 9.97. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.806 |
| KXB80417.1 | KXB80419.1 | HMPREF1860_00333 | HMPREF1860_00335 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96. | 0.820 |
| KXB80417.1 | KXB80420.1 | HMPREF1860_00333 | HMPREF1860_00336 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.820 |
| KXB80417.1 | metK | HMPREF1860_00333 | HMPREF1860_00337 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.820 |
| KXB80417.1 | rnpA | HMPREF1860_00333 | HMPREF1860_00334 | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | Putative ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.986 |
| KXB80419.1 | KXB80417.1 | HMPREF1860_00335 | HMPREF1860_00333 | uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.820 |
| KXB80419.1 | KXB80420.1 | HMPREF1860_00335 | HMPREF1860_00336 | uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | 0.820 |
| KXB80419.1 | metK | HMPREF1860_00335 | HMPREF1860_00337 | uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.839 |
| KXB80419.1 | rnpA | HMPREF1860_00335 | HMPREF1860_00334 | uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96. | Putative ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.915 |
| KXB80420.1 | KXB80417.1 | HMPREF1860_00336 | HMPREF1860_00333 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.820 |
| KXB80420.1 | KXB80419.1 | HMPREF1860_00336 | HMPREF1860_00335 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96. | 0.820 |
| KXB80420.1 | metK | HMPREF1860_00336 | HMPREF1860_00337 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.820 |
| KXB80420.1 | rnpA | HMPREF1860_00336 | HMPREF1860_00334 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00. | Putative ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.820 |
| fcl | metK | HMPREF1860_00049 | HMPREF1860_00337 | NAD dependent epimerase/dehydratase family protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.806 |
| metK | KXB75702.1 | HMPREF1860_00337 | HMPREF1860_01743 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | NAD dependent epimerase/dehydratase family protein; KEGG: sgo:SGO_2016 1.7e-71 nucleotide sugar dehydratase K01710; Psort location: Cytoplasmic, score: 9.26. | 0.806 |
| metK | KXB78055.1 | HMPREF1860_00337 | HMPREF1860_01097 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | KEGG: pdn:HMPREF9137_0844 1.2e-134 NAD dependent epimerase/dehydratase family protein; Psort location: Cytoplasmic, score: 8.96. | 0.806 |
| metK | KXB80113.1 | HMPREF1860_00337 | HMPREF1860_00399 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | KEGG: abu:Abu_1481 3.9e-72 DNA (cytosine-5-)-methyltransferase K00558; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. | 0.843 |