Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (430 aa)    
Predicted Functional Partners:
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
 
 0.936
KXB80113.1
KEGG: abu:Abu_1481 3.9e-72 DNA (cytosine-5-)-methyltransferase K00558; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.843
KXB80419.1
uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96.
     
 0.839
KXB80417.1
Hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
       0.820
rnpA
Putative ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
       0.820
KXB80420.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.820
fcl
NAD dependent epimerase/dehydratase family protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
   
 0.806
KXB80393.1
NAD dependent epimerase/dehydratase family protein; KEGG: bfs:BF4355 1.5e-102 UDP-glucose 4-epimerase K01784; Psort location: Cytoplasmic, score: 9.97.
   
 0.806
KXB78055.1
KEGG: pdn:HMPREF9137_0844 1.2e-134 NAD dependent epimerase/dehydratase family protein; Psort location: Cytoplasmic, score: 8.96.
   
 0.806
KXB75702.1
NAD dependent epimerase/dehydratase family protein; KEGG: sgo:SGO_2016 1.7e-71 nucleotide sugar dehydratase K01710; Psort location: Cytoplasmic, score: 9.26.
   
 0.806
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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