Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
miaBtRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (442 aa)    
Predicted Functional Partners:
KXB80424.1
KEGG: pmz:HMPREF0659_A6394 1.8e-280 putative Lipid A export ATP-binding/permease protein MsbA; K11085 ATP-binding cassette, subfamily B, bacterial MsbA; Psort location: CytoplasmicMembrane, score: 10.00.
       0.673
KXB80423.1
Arylsulfatase; KEGG: pit:PIN17_A0668 2.2e-234 arylsulfatase; Psort location: CytoplasmicMembrane, score: 10.00.
  
    0.656
rlmN
23S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.609
KXB80426.1
Putative collagenase; KEGG: pmz:HMPREF0659_A6397 3.2e-187 peptidase, U32 family K08303; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.577
KXB80428.1
RNA methyltransferase, TrmH family; KEGG: ccm:Ccan_04200 2.8e-46 23S rRNA Gm2251 2'-O-methyltransferase; Psort location: Cytoplasmic, score: 8.96.
   
   0.558
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
  
 0.550
KXB80427.1
Fe-S metabolism associated domain protein; KEGG: vvu:VV1_1803 9.3e-23 csdE; cysteine desulfurase K02426; Psort location: Cytoplasmic, score: 9.26.
       0.492
KXB80419.1
uroporphyrinogen-III synthase; KEGG: pdn:HMPREF9137_0433 2.5e-107 hemD; uroporphyrinogen-III synthase K01719; Psort location: Cytoplasmic, score: 8.96.
     
 0.472
miaA-2
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
 
  
 0.470
KXB81932.1
Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
 
   
 0.450
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.