Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB80272.1RNA polymerase sigma factor RpoD family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (290 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.884
KXB78294.1
Sigma-70, region 4; KEGG: lru:HMPREF0538_21998 4.5e-23 rpoD; DNA-directed RNA polymerase sigma subunit RpoD K03086; Psort location: Cytoplasmic, score: 9.97; Belongs to the sigma-70 factor family.
  
  
 
0.866
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.855
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.825
KXB80146.1
Hypothetical protein.
   
 
 0.781
KXB75706.1
HTH domain protein; Psort location: Cytoplasmic, score: 8.96.
    
   0.743
KXB78068.1
KEGG: pfe:PSF113_2023 1.0e-09 MerR family transcriptional regulator.
 
 
 0.727
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.701
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
 
 0.697
KXB79131.1
Putative oxidative stress regulatory protein OxyR; KEGG: mct:MCR_0286 1.1e-42 LysR family transcriptional regulator K04761; Psort location: Cytoplasmic, score: 9.97; Belongs to the LysR transcriptional regulatory family.
   
 
 0.691
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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