Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB80275.1Putative permease; KEGG: swp:swp_1190 8.9e-89 xanthine/uracil/vitamin C permease K06901; Psort location: CytoplasmicMembrane, score: 10.00. (433 aa)    
Predicted Functional Partners:
purL
Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.871
KXB80274.1
Putative NAD(+) diphosphatase; KEGG: pmz:HMPREF0659_A5588 5.2e-100 hydrolase, NUDIX family; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 8.96.
       0.817
KXB80273.1
5'-nucleotidase protein; KEGG: pmz:HMPREF0659_A5589 5.8e-236 5'-nucleotidase, C-terminal domain protein; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
       0.722
KXB74290.1
KEGG: pmz:HMPREF0659_A7303 5.5e-112 putative glycerate dehydrogenase; K00018 glycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 0.557
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.536
purD
KEGG: pmz:HMPREF0659_A6752 2.4e-175 purD; phosphoribosylamine--glycine ligase K01945; Psort location: Cytoplasmic, score: 9.97; Belongs to the GARS family.
  
  
 0.509
purE
Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.489
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.482
purC
KEGG: pmz:HMPREF0659_A6716 1.9e-150 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family.
  
  
 0.460
KXB79097.1
Hypothetical protein; KEGG: pmz:HMPREF0659_A6730 2.4e-182 hypothetical protein; K01933 phosphoribosylformylglycinamidine cyclo-ligase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.459
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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