| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB75996.1 | KXB79979.1 | HMPREF1860_01665 | HMPREF1860_00484 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.507 |
| KXB77266.1 | KXB79979.1 | HMPREF1860_01436 | HMPREF1860_00484 | Sigma-54 interaction domain protein; KEGG: pfe:PSF113_0046 1.1e-65 algB; protein AlgB; Psort location: Cytoplasmic, score: 9.97. | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.513 |
| KXB77266.1 | ribBA | HMPREF1860_01436 | HMPREF1860_02144 | Sigma-54 interaction domain protein; KEGG: pfe:PSF113_0046 1.1e-65 algB; protein AlgB; Psort location: Cytoplasmic, score: 9.97. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.568 |
| KXB77325.1 | KXB79979.1 | HMPREF1860_01495 | HMPREF1860_00484 | KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.555 |
| KXB77325.1 | KXB80382.1 | HMPREF1860_01495 | HMPREF1860_00298 | KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.647 |
| KXB77325.1 | guaA | HMPREF1860_01495 | HMPREF1860_00170 | KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.841 |
| KXB79978.1 | KXB79979.1 | HMPREF1860_00483 | HMPREF1860_00484 | Hypothetical protein. | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.799 |
| KXB79978.1 | rnz | HMPREF1860_00483 | HMPREF1860_00482 | Hypothetical protein. | Putative ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.849 |
| KXB79978.1 | valS | HMPREF1860_00483 | HMPREF1860_00485 | Hypothetical protein. | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.668 |
| KXB79979.1 | KXB75996.1 | HMPREF1860_00484 | HMPREF1860_01665 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.507 |
| KXB79979.1 | KXB77266.1 | HMPREF1860_00484 | HMPREF1860_01436 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Sigma-54 interaction domain protein; KEGG: pfe:PSF113_0046 1.1e-65 algB; protein AlgB; Psort location: Cytoplasmic, score: 9.97. | 0.513 |
| KXB79979.1 | KXB77325.1 | HMPREF1860_00484 | HMPREF1860_01495 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.555 |
| KXB79979.1 | KXB79978.1 | HMPREF1860_00484 | HMPREF1860_00483 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein. | 0.799 |
| KXB79979.1 | KXB80382.1 | HMPREF1860_00484 | HMPREF1860_00298 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.505 |
| KXB79979.1 | era | HMPREF1860_00484 | HMPREF1860_00885 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.655 |
| KXB79979.1 | guaA | HMPREF1860_00484 | HMPREF1860_00170 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.573 |
| KXB79979.1 | ribBA | HMPREF1860_00484 | HMPREF1860_02144 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.600 |
| KXB79979.1 | rnz | HMPREF1860_00484 | HMPREF1860_00482 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | Putative ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.799 |
| KXB79979.1 | valS | HMPREF1860_00484 | HMPREF1860_00485 | MazG family protein; KEGG: pit:PIN17_A1669 1.2e-116 MazG family protein; K02428 dITP/XTP pyrophosphatase; Psort location: Cytoplasmic, score: 8.96. | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.698 |
| KXB80382.1 | KXB77325.1 | HMPREF1860_00298 | HMPREF1860_01495 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.647 |