Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB79499.1Ribose-5-phosphate isomerase B; KEGG: pdn:HMPREF9137_1889 2.0e-68 putative ribose-5-phosphate isomerase B; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 8.96. (146 aa)    
Predicted Functional Partners:
KXB79500.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: pmz:HMPREF0659_A6472 4.0e-299 putative transketolase; K00615 transketolase; Psort location: Cytoplasmic, score: 9.26; Belongs to the transketolase family.
    
 0.959
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.948
KXB74200.1
KEGG: pdn:HMPREF9137_1184 5.8e-85 rpe; ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 9.26.
 
 
 0.913
KXB81950.1
KEGG: pmz:HMPREF0659_A6685 5.6e-151 prs; ribose-phosphate diphosphokinase K00948; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.893
KXB75989.1
Putative phosphoglucomutase; KEGG: pdn:HMPREF9137_2410 2.2e-266 pgcA; phosphoglucomutase; Psort location: Cytoplasmic, score: 8.96.
     
 0.847
pdxT
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
     
  0.841
pdxS
Pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
     
  0.841
KXB78030.1
Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
    
 0.734
KXB78942.1
KEGG: pdn:HMPREF9137_0478 9.9e-106 uracil phosphoribosyltransferase K00761; Psort location: Cytoplasmic, score: 9.97.
 
    0.721
KXB81393.1
KEGG: pmz:HMPREF0659_A6293 1.4e-83 prmC; protein-(glutamine-N5) methyltransferase, release factor-specific K02493; Psort location: Cytoplasmic, score: 9.97.
      0.679
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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