| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74392.1 | KXB81394.1 | HMPREF1860_02033 | HMPREF1860_00168 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.600 |
| KXB74392.1 | panB | HMPREF1860_02033 | HMPREF1860_00660 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.489 |
| KXB74392.1 | panC | HMPREF1860_02033 | HMPREF1860_02175 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.910 |
| KXB74392.1 | panD | HMPREF1860_02033 | HMPREF1860_02174 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.537 |
| KXB78133.1 | panB | HMPREF1860_01176 | HMPREF1860_00660 | KEGG: pdn:HMPREF9137_1664 8.7e-162 ilvE; branched-chain-amino-acid transaminase K00826; Psort location: Cytoplasmic, score: 9.97. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.859 |
| KXB78555.1 | panB | HMPREF1860_00922 | HMPREF1860_00660 | Hypothetical protein; KEGG: ccm:Ccan_10160 1.0e-39 putative Pyrroline-5-carboxylate reductase; Psort location: Cytoplasmic, score: 8.96. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.712 |
| KXB78555.1 | panC | HMPREF1860_00922 | HMPREF1860_02175 | Hypothetical protein; KEGG: ccm:Ccan_10160 1.0e-39 putative Pyrroline-5-carboxylate reductase; Psort location: Cytoplasmic, score: 8.96. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.697 |
| KXB79117.1 | panB | HMPREF1860_00661 | HMPREF1860_00660 | Transporter, major facilitator family protein; KEGG: wch:wcw_0031 0.0046 hypothetical protein; K05939 acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase; Psort location: CytoplasmicMembrane, score: 10.00. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.694 |
| KXB79899.1 | KXB81394.1 | HMPREF1860_00500 | HMPREF1860_00168 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.551 |
| KXB79899.1 | panB | HMPREF1860_00500 | HMPREF1860_00660 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.677 |
| KXB79899.1 | panD | HMPREF1860_00500 | HMPREF1860_02174 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.467 |
| KXB81394.1 | KXB74392.1 | HMPREF1860_00168 | HMPREF1860_02033 | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.600 |
| KXB81394.1 | KXB79899.1 | HMPREF1860_00168 | HMPREF1860_00500 | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.551 |
| KXB81394.1 | guaA | HMPREF1860_00168 | HMPREF1860_00170 | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.816 |
| KXB81394.1 | panB | HMPREF1860_00168 | HMPREF1860_00660 | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.475 |
| KXB81394.1 | panC | HMPREF1860_00168 | HMPREF1860_02175 | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.479 |
| guaA | KXB81394.1 | HMPREF1860_00170 | HMPREF1860_00168 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.816 |
| guaA | msrA | HMPREF1860_00170 | HMPREF1860_01476 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.419 |
| guaA | panB | HMPREF1860_00170 | HMPREF1860_00660 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.600 |
| guaA | panC | HMPREF1860_00170 | HMPREF1860_02175 | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.488 |