Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (272 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.997
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.883
KXB78133.1
KEGG: pdn:HMPREF9137_1664 8.7e-162 ilvE; branched-chain-amino-acid transaminase K00826; Psort location: Cytoplasmic, score: 9.97.
    
 0.859
KXB78555.1
Hypothetical protein; KEGG: ccm:Ccan_10160 1.0e-39 putative Pyrroline-5-carboxylate reductase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.712
KXB79117.1
Transporter, major facilitator family protein; KEGG: wch:wcw_0031 0.0046 hypothetical protein; K05939 acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid--[acyl-carrier-protein] ligase; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.694
KXB79899.1
KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family.
      0.677
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.600
KXB74392.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
   
 0.489
KXB81394.1
KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97.
     
 0.475
msrA
methionine-R-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.413
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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