| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74391.1 | KXB74394.1 | HMPREF1860_02032 | HMPREF1860_02035 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.669 |
| KXB74391.1 | dnaA | HMPREF1860_02032 | HMPREF1860_00671 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.403 |
| KXB74391.1 | mfd | HMPREF1860_02032 | HMPREF1860_01098 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.528 |
| KXB74391.1 | pheT | HMPREF1860_02032 | HMPREF1860_02059 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | KEGG: pmz:HMPREF0659_A6941 0. pheT; phenylalanine--tRNA ligase, beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.525 |
| KXB74391.1 | polA | HMPREF1860_02032 | HMPREF1860_00085 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.531 |
| KXB74391.1 | recF | HMPREF1860_02032 | HMPREF1860_00732 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.564 |
| KXB74391.1 | recR | HMPREF1860_02032 | HMPREF1860_00592 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.407 |
| KXB74394.1 | KXB74391.1 | HMPREF1860_02035 | HMPREF1860_02032 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.669 |
| KXB74394.1 | dnaA | HMPREF1860_02035 | HMPREF1860_00671 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.975 |
| KXB74394.1 | mfd | HMPREF1860_02035 | HMPREF1860_01098 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.441 |
| KXB74394.1 | pheT | HMPREF1860_02035 | HMPREF1860_02059 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: pmz:HMPREF0659_A6941 0. pheT; phenylalanine--tRNA ligase, beta subunit K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.448 |
| KXB74394.1 | polA | HMPREF1860_02035 | HMPREF1860_00085 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
| KXB74394.1 | recF | HMPREF1860_02035 | HMPREF1860_00732 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.784 |
| KXB79100.1 | KXB79102.1 | HMPREF1860_00731 | HMPREF1860_00733 | Hypothetical protein. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.0016 TPR repeat-containing serine/threonine protein kinase K00908. | 0.636 |
| KXB79100.1 | recF | HMPREF1860_00731 | HMPREF1860_00732 | Hypothetical protein. | Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.836 |
| KXB79100.1 | ribH | HMPREF1860_00731 | HMPREF1860_00734 | Hypothetical protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.641 |
| KXB79102.1 | KXB79100.1 | HMPREF1860_00733 | HMPREF1860_00731 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.0016 TPR repeat-containing serine/threonine protein kinase K00908. | Hypothetical protein. | 0.636 |
| KXB79102.1 | recF | HMPREF1860_00733 | HMPREF1860_00732 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.0016 TPR repeat-containing serine/threonine protein kinase K00908. | Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.643 |
| KXB79102.1 | ribH | HMPREF1860_00733 | HMPREF1860_00734 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.0016 TPR repeat-containing serine/threonine protein kinase K00908. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.829 |
| dnaA | KXB74391.1 | HMPREF1860_00671 | HMPREF1860_02032 | Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.403 |
