STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB78972.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. (646 aa)    
Predicted Functional Partners:
KXB76235.1
KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.965
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 0.939
KXB77397.1
Hypothetical protein; KEGG: efc:EFAU004_01897 0.00078 IS1380 family transposase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.824
KXB76963.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.824
KXB75442.1
Transposase, IS4 family; KEGG: efc:EFAU004_01897 0.0036 IS1380 family transposase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.824
KXB75028.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.824
KXB74966.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
  
 
 0.824
KXB78971.1
Hypothetical protein; KEGG: ccs:CCNA_01212 1.1e-16 dATP pyrophosphohydrolase; Psort location: Periplasmic, score: 9.51.
     
 0.735
KXB78973.1
Peptidase, S41 family; KEGG: pdn:HMPREF9137_0624 8.5e-203 peptidase, S41 family K03797; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the peptidase S41A family.
       0.711
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
   0.601
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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