STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB78901.1KEGG: bhl:Bache_2554 4.3e-247 type I restriction-modification system, M subunit; K03427 type I restriction enzyme M protein. (515 aa)    
Predicted Functional Partners:
KXB78904.1
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
 
 0.994
KXB78902.1
KEGG: hpj:jhp0726 6.5e-86 hsdS_4; type I restriction enzyme (specificity subunit); K01154 type I restriction enzyme, S subunit; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.991
KXB79507.1
Hypothetical protein; KEGG: fte:Fluta_2981 1.0e-09 restriction modification system DNA specificity domain-containing protein; K01154 type I restriction enzyme, S subunit.
 
 
 0.941
KXB78903.1
KEGG: hie:R2846_0421 2.0e-107 prrC; Anticodon nuclease; Psort location: Cytoplasmic, score: 8.96.
 
     0.911
KXB78905.1
Toxin-antitoxin system, toxin component, Fic family; KEGG: pdn:HMPREF9137_0457 1.1e-26 purC_2; phosphoribosylaminoimidazole succinocarboxamide synthase; Psort location: Cytoplasmic, score: 8.96.
  
    0.660
KXB74244.1
Type I restriction enzyme HsdR protein; KEGG: nth:Nther_0809 3.8e-05 LexA repressor; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.506
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.483
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
   0.407
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.