Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB78777.1Type III restriction enzyme, res subunit; KEGG: mph:MLP_35860 2.0e-171 putative helicase. (547 aa)    
Predicted Functional Partners:
KXB78778.1
DNA (cytosine-5-)-methyltransferase; KEGG: bfs:BF1120 7.0e-176 modification enzyme of type III restriction-modification system; K00571 site-specific DNA-methyltransferase (adenine-specific); Psort location: Cytoplasmic, score: 8.96.
 
   
 0.883
KXB78780.1
Type III restriction enzyme, res subunit; KEGG: pah:Poras_0991 0. type III site-specific deoxyribonuclease; Psort location: Cytoplasmic, score: 8.96.
 
     0.882
KXB78776.1
DNA-binding helix-turn-helix protein.
       0.782
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.754
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.678
KXB80146.1
Hypothetical protein.
    
 0.677
KXB79112.1
UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 7.4e-291 UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.675
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.675
KXB74394.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.675
KXB81943.1
Tetratricopeptide repeat domain protein; KEGG: ccm:Ccan_18230 2.0e-91 PIF1/RRM3 DNA helicase-like protein; Psort location: Cytoplasmic, score: 8.96.
   
 0.652
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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