Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (554 aa)    
Predicted Functional Partners:
KXB78449.1
KEGG: pit:PIN17_A1106 2.8e-85 isochorismate synthase K02361.
 
 
 0.997
KXB78446.1
KEGG: pmz:HMPREF0659_A6052 2.7e-135 menC; o-succinylbenzoate synthase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.954
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA).
 
  
 0.951
KXB78445.1
O-succinylbenzoic acid--CoA ligase family protein; KEGG: pit:PIN17_A1102 4.2e-107 AMP-binding enzyme domain protein; K01911 O-succinylbenzoic acid--CoA ligase; Psort location: Cytoplasmic, score: 8.96.
 
   
 0.918
KXB78450.1
Hypothetical protein; KEGG: tsc:TSC_c18630 3.2e-13 ydiI; esterase YdiI.
 
   
 0.857
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.799
KXB75994.1
KEGG: osp:Odosp_0584 6.7e-84 Aminodeoxychorismate synthase K01665; Psort location: Cytoplasmic, score: 9.97.
     
 0.429
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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