| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74137.1 | KXB78030.1 | HMPREF1860_02127 | HMPREF1860_01072 | Malic enzyme, NAD binding domain protein; KEGG: pmz:HMPREF0659_A6863 1.2e-187 malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97. | Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96. | 0.970 |
| KXB74137.1 | nadE | HMPREF1860_02127 | HMPREF1860_00966 | Malic enzyme, NAD binding domain protein; KEGG: pmz:HMPREF0659_A6863 1.2e-187 malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.860 |
| KXB74137.1 | nadK | HMPREF1860_02127 | HMPREF1860_00519 | Malic enzyme, NAD binding domain protein; KEGG: pmz:HMPREF0659_A6863 1.2e-187 malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.647 |
| KXB74137.1 | purL | HMPREF1860_02127 | HMPREF1860_01737 | Malic enzyme, NAD binding domain protein; KEGG: pmz:HMPREF0659_A6863 1.2e-187 malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97. | Putative phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.583 |
| KXB75996.1 | KXB77494.1 | HMPREF1860_01665 | HMPREF1860_01391 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.936 |
| KXB75996.1 | KXB78030.1 | HMPREF1860_01665 | HMPREF1860_01072 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96. | 0.599 |
| KXB75996.1 | KXB79899.1 | HMPREF1860_01665 | HMPREF1860_00500 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.957 |
| KXB75996.1 | KXB80274.1 | HMPREF1860_01665 | HMPREF1860_00357 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Putative NAD(+) diphosphatase; KEGG: pmz:HMPREF0659_A5588 5.2e-100 hydrolase, NUDIX family; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.847 |
| KXB75996.1 | KXB80833.1 | HMPREF1860_01665 | HMPREF1860_00266 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Hypothetical protein. | 0.533 |
| KXB75996.1 | nadD | HMPREF1860_01665 | HMPREF1860_01369 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.945 |
| KXB75996.1 | nadE | HMPREF1860_01665 | HMPREF1860_00966 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.813 |
| KXB77494.1 | KXB75996.1 | HMPREF1860_01391 | HMPREF1860_01665 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.936 |
| KXB77494.1 | KXB78030.1 | HMPREF1860_01391 | HMPREF1860_01072 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96. | 0.400 |
| KXB77494.1 | KXB79899.1 | HMPREF1860_01391 | HMPREF1860_00500 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.914 |
| KXB77494.1 | KXB80274.1 | HMPREF1860_01391 | HMPREF1860_00357 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Putative NAD(+) diphosphatase; KEGG: pmz:HMPREF0659_A5588 5.2e-100 hydrolase, NUDIX family; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 8.96. | 0.863 |
| KXB77494.1 | KXB80833.1 | HMPREF1860_01391 | HMPREF1860_00266 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Hypothetical protein. | 0.735 |
| KXB77494.1 | nadD | HMPREF1860_01391 | HMPREF1860_01369 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.940 |
| KXB77494.1 | nadE | HMPREF1860_01391 | HMPREF1860_00966 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.916 |
| KXB77494.1 | nadK | HMPREF1860_01391 | HMPREF1860_00519 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.572 |
| KXB78030.1 | KXB74137.1 | HMPREF1860_01072 | HMPREF1860_02127 | Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96. | Malic enzyme, NAD binding domain protein; KEGG: pmz:HMPREF0659_A6863 1.2e-187 malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97. | 0.970 |