STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB78228.1KEGG: pit:PIN17_A1822 3.4e-144 ftcD; glutamate formimidoyltransferase; Psort location: Cytoplasmic, score: 8.96. (353 aa)    
Predicted Functional Partners:
fhs
Formate--tetrahydrofolate ligase; KEGG: pmz:HMPREF0659_A6755 1.2e-228 fhs; formate--tetrahydrofolate ligase K01938; Psort location: Cytoplasmic, score: 8.96.
    
 0.782
folD
Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.751
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.685
KXB74200.1
KEGG: pdn:HMPREF9137_1184 5.8e-85 rpe; ribulose-phosphate 3-epimerase K01783; Psort location: Cytoplasmic, score: 9.26.
 
      0.685
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
    
 0.684
KXB77798.1
Aminotransferase, class I/II; KEGG: pmz:HMPREF0659_A6793 2.1e-174 aminotransferase, class I/II K00812; Psort location: Cytoplasmic, score: 9.97.
 
 
  0.671
KXB77330.1
AICARFT/IMPCHase bienzyme; KEGG: pmz:HMPREF0659_A5388 1.1e-188 AICARFT/IMPCHase bienzyme; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase.
    
  0.643
KXB79946.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.638
KXB78033.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; KEGG: lbi:LEPBI_I0539 4.7e-28 SDR family dehydrogenase; Psort location: Cytoplasmic, score: 9.26.
    
 0.624
KXB79592.1
Glutamate--ammonia ligase, catalytic domain protein; KEGG: pdn:HMPREF9137_1467 1.7e-206 putative glutamine synthetase, beta-grasp domain-containing protein; K01915 glutamine synthetase; Psort location: Cytoplasmic, score: 9.97.
    
  0.604
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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