STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB78121.1Magnesium transporter; Acts as a magnesium transporter. (460 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.749
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.603
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.490
KXB81399.1
TrkA protein; KEGG: cnc:CNE_1c04080 5.4e-33 kdsD; arabinose 5-phosphate isomerase KdsD K03455; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.452
KXB79922.1
KEGG: rcp:RCAP_rcc01550 2.1e-21 M23 family peptidase; Psort location: OuterMembrane, score: 9.93.
   
  0.441
KXB80382.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.436
KXB80273.1
5'-nucleotidase protein; KEGG: pmz:HMPREF0659_A5589 5.8e-236 5'-nucleotidase, C-terminal domain protein; K01119 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
    
  0.414
KXB77334.1
KEGG: ccm:Ccan_10800 1.4e-21 5'-Nucleotidase domain-containing protein.
    
  0.414
KXB77335.1
Ser/Thr phosphatase family protein; KEGG: bsa:Bacsa_3012 1.1e-76 5'-nucleotidase; Psort location: Periplasmic, score: 9.76.
    
  0.414
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.