Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KXB77455.1KEGG: pdn:HMPREF9137_0880 1.7e-149 lactate/malate dehydrogenase, NAD binding domain-containing protein; K00024 malate dehydrogenase; Psort location: Cytoplasmic, score: 9.26; Belongs to the LDH/MDH superfamily. (328 aa)    
Predicted Functional Partners:
KXB76224.1
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.993
KXB78030.1
Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
  
 0.991
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
  
 0.957
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.943
KXB74137.1
Malic enzyme, NAD binding domain protein; KEGG: pmz:HMPREF0659_A6863 1.2e-187 malate dehydrogenase (oxaloacetate-decarboxylating) K00029; Psort location: Cytoplasmic, score: 9.97.
  
 0.943
KXB79506.1
Pyruvate kinase; KEGG: pdn:HMPREF9137_0096 1.9e-189 pyk; pyruvate kinase K00873; Psort location: Cytoplasmic, score: 9.97.
  
 0.935
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 0.933
KXB80136.1
KEGG: pmz:HMPREF0659_A5403 7.4e-149 putative aspartate transaminase; K00812 aspartate aminotransferase; Psort location: Cytoplasmic, score: 9.26.
  
 0.905
KXB77798.1
Aminotransferase, class I/II; KEGG: pmz:HMPREF0659_A6793 2.1e-174 aminotransferase, class I/II K00812; Psort location: Cytoplasmic, score: 9.97.
  
 0.905
KXB77322.1
Glutamate dehydrogenase, NAD-specific; KEGG: pit:PIN17_A1094 9.6e-227 gdh; glutamate dehydrogenase K00262; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.892
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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