| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB75996.1 | KXB77494.1 | HMPREF1860_01665 | HMPREF1860_01391 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.810 |
| KXB75996.1 | KXB79899.1 | HMPREF1860_01665 | HMPREF1860_00500 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.848 |
| KXB75996.1 | KXB81394.1 | HMPREF1860_01665 | HMPREF1860_00168 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.459 |
| KXB75996.1 | nadD | HMPREF1860_01665 | HMPREF1860_01369 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.867 |
| KXB75996.1 | nadE | HMPREF1860_01665 | HMPREF1860_00966 | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.748 |
| KXB77474.1 | coaD | HMPREF1860_01371 | HMPREF1860_00330 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.557 |
| KXB77474.1 | gmk | HMPREF1860_01371 | HMPREF1860_01370 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.874 |
| KXB77474.1 | nadD | HMPREF1860_01371 | HMPREF1860_01369 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.716 |
| KXB77494.1 | KXB75996.1 | HMPREF1860_01391 | HMPREF1860_01665 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.810 |
| KXB77494.1 | KXB79899.1 | HMPREF1860_01391 | HMPREF1860_00500 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | 0.808 |
| KXB77494.1 | KXB81394.1 | HMPREF1860_01391 | HMPREF1860_00168 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.416 |
| KXB77494.1 | coaD | HMPREF1860_01391 | HMPREF1860_00330 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.406 |
| KXB77494.1 | nadD | HMPREF1860_01391 | HMPREF1860_01369 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.866 |
| KXB77494.1 | nadE | HMPREF1860_01391 | HMPREF1860_00966 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.895 |
| KXB77494.1 | nadK | HMPREF1860_01391 | HMPREF1860_00519 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.471 |
| KXB77494.1 | rsfS | HMPREF1860_01391 | HMPREF1860_01115 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.643 |
| KXB79899.1 | KXB75996.1 | HMPREF1860_00500 | HMPREF1860_01665 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.848 |
| KXB79899.1 | KXB77494.1 | HMPREF1860_00500 | HMPREF1860_01391 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.808 |
| KXB79899.1 | KXB81394.1 | HMPREF1860_00500 | HMPREF1860_00168 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.466 |
| KXB79899.1 | nadD | HMPREF1860_00500 | HMPREF1860_01369 | KEGG: pit:PIN17_A1852 9.0e-128 nadC; nicotinate-nucleotide diphosphorylase K00767; Psort location: Cytoplasmic, score: 9.97; Belongs to the NadC/ModD family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.864 |