| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74342.1 | KXB77475.1 | HMPREF1860_02080 | HMPREF1860_01372 | Hydrolase, P-loop family; KEGG: efc:EFAU004_00653 1.1e-17 ATPase K06925; Psort location: Cytoplasmic, score: 9.97. | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | 0.946 |
| KXB74342.1 | tsaD | HMPREF1860_02080 | HMPREF1860_01390 | Hydrolase, P-loop family; KEGG: efc:EFAU004_00653 1.1e-17 ATPase K06925; Psort location: Cytoplasmic, score: 9.97. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.876 |
| KXB77474.1 | KXB77475.1 | HMPREF1860_01371 | HMPREF1860_01372 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | 0.790 |
| KXB77474.1 | KXB77476.1 | HMPREF1860_01371 | HMPREF1860_01373 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.655 |
| KXB77474.1 | dxr | HMPREF1860_01371 | HMPREF1860_01376 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.585 |
| KXB77474.1 | gmk | HMPREF1860_01371 | HMPREF1860_01370 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.874 |
| KXB77474.1 | murA | HMPREF1860_01371 | HMPREF1860_01374 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.653 |
| KXB77474.1 | nadD | HMPREF1860_01371 | HMPREF1860_01369 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.716 |
| KXB77474.1 | rimM | HMPREF1860_01371 | HMPREF1860_01375 | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.636 |
| KXB77475.1 | KXB74342.1 | HMPREF1860_01372 | HMPREF1860_02080 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | Hydrolase, P-loop family; KEGG: efc:EFAU004_00653 1.1e-17 ATPase K06925; Psort location: Cytoplasmic, score: 9.97. | 0.946 |
| KXB77475.1 | KXB77474.1 | HMPREF1860_01372 | HMPREF1860_01371 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | 0.790 |
| KXB77475.1 | KXB77476.1 | HMPREF1860_01372 | HMPREF1860_01373 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.766 |
| KXB77475.1 | KXB81394.1 | HMPREF1860_01372 | HMPREF1860_00168 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.646 |
| KXB77475.1 | dxr | HMPREF1860_01372 | HMPREF1860_01376 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.652 |
| KXB77475.1 | gmk | HMPREF1860_01372 | HMPREF1860_01370 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.637 |
| KXB77475.1 | murA | HMPREF1860_01372 | HMPREF1860_01374 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.769 |
| KXB77475.1 | nadD | HMPREF1860_01372 | HMPREF1860_01369 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.677 |
| KXB77475.1 | rimM | HMPREF1860_01372 | HMPREF1860_01375 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | 16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.748 |
| KXB77475.1 | tsaD | HMPREF1860_01372 | HMPREF1860_01390 | KEGG: osp:Odosp_1555 4.6e-53 universal protein YeaZ; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 8.96. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.960 |
| KXB77476.1 | KXB77474.1 | HMPREF1860_01373 | HMPREF1860_01371 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: pfe:PSF113_5769 7.1e-25 yicC; protein YicC; Psort location: Cytoplasmic, score: 9.97. | 0.655 |