| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB77489.1 | KXB77490.1 | HMPREF1860_01386 | HMPREF1860_01387 | Arylsulfatase; KEGG: pdn:HMPREF9137_0720 2.1e-128 arylsulfatase; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.480 |
| KXB77489.1 | smpB | HMPREF1860_01386 | HMPREF1860_01388 | Arylsulfatase; KEGG: pdn:HMPREF9137_0720 2.1e-128 arylsulfatase; Psort location: CytoplasmicMembrane, score: 10.00. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.480 |
| KXB77490.1 | KXB77489.1 | HMPREF1860_01387 | HMPREF1860_01386 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Arylsulfatase; KEGG: pdn:HMPREF9137_0720 2.1e-128 arylsulfatase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.480 |
| KXB77490.1 | KXB77494.1 | HMPREF1860_01387 | HMPREF1860_01391 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.535 |
| KXB77490.1 | map | HMPREF1860_01387 | HMPREF1860_01389 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.627 |
| KXB77490.1 | smpB | HMPREF1860_01387 | HMPREF1860_01388 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.820 |
| KXB77490.1 | tsaD | HMPREF1860_01387 | HMPREF1860_01390 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.595 |
| KXB77494.1 | KXB77490.1 | HMPREF1860_01391 | HMPREF1860_01387 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.535 |
| KXB77494.1 | map | HMPREF1860_01391 | HMPREF1860_01389 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.638 |
| KXB77494.1 | smpB | HMPREF1860_01391 | HMPREF1860_01388 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.535 |
| KXB77494.1 | tsaD | HMPREF1860_01391 | HMPREF1860_01390 | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.673 |
| map | KXB77490.1 | HMPREF1860_01389 | HMPREF1860_01387 | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.627 |
| map | KXB77494.1 | HMPREF1860_01389 | HMPREF1860_01391 | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.638 |
| map | smpB | HMPREF1860_01389 | HMPREF1860_01388 | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.653 |
| map | tsaD | HMPREF1860_01389 | HMPREF1860_01390 | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.813 |
| smpB | KXB77489.1 | HMPREF1860_01388 | HMPREF1860_01386 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Arylsulfatase; KEGG: pdn:HMPREF9137_0720 2.1e-128 arylsulfatase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.480 |
| smpB | KXB77490.1 | HMPREF1860_01388 | HMPREF1860_01387 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.820 |
| smpB | KXB77494.1 | HMPREF1860_01388 | HMPREF1860_01391 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Competence/damage-inducible protein CinA domain protein; KEGG: cco:CCC13826_0279 1.3e-17 fadD; long-chain-fatty-acid--CoA ligase K03743; Psort location: Cytoplasmic, score: 8.96; Belongs to the CinA family. | 0.535 |
| smpB | map | HMPREF1860_01388 | HMPREF1860_01389 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.653 |
| smpB | tsaD | HMPREF1860_01388 | HMPREF1860_01390 | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.616 |
