| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB77307.1 | KXB77366.1 | HMPREF1860_01477 | HMPREF1860_01423 | Thioredoxin-disulfide reductase; KEGG: pmz:HMPREF0659_A6627 2.7e-135 trxB; thioredoxin-disulfide reductase K00384; Psort location: Cytoplasmic, score: 9.97. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.498 |
| KXB77307.1 | glyA | HMPREF1860_01477 | HMPREF1860_00619 | Thioredoxin-disulfide reductase; KEGG: pmz:HMPREF0659_A6627 2.7e-135 trxB; thioredoxin-disulfide reductase K00384; Psort location: Cytoplasmic, score: 9.97. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.561 |
| KXB77365.1 | KXB77366.1 | HMPREF1860_01422 | HMPREF1860_01423 | Hypothetical protein. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.542 |
| KXB77366.1 | KXB77307.1 | HMPREF1860_01423 | HMPREF1860_01477 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Thioredoxin-disulfide reductase; KEGG: pmz:HMPREF0659_A6627 2.7e-135 trxB; thioredoxin-disulfide reductase K00384; Psort location: Cytoplasmic, score: 9.97. | 0.498 |
| KXB77366.1 | KXB77365.1 | HMPREF1860_01423 | HMPREF1860_01422 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein. | 0.542 |
| KXB77366.1 | KXB77367.1 | HMPREF1860_01423 | HMPREF1860_01424 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein. | 0.548 |
| KXB77366.1 | KXB77468.1 | HMPREF1860_01423 | HMPREF1860_01365 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Prenyltransferase, UbiA family; KEGG: ctc:CTC01291 5.8e-46 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the UbiA prenyltransferase family. | 0.599 |
| KXB77366.1 | KXB78123.1 | HMPREF1860_01423 | HMPREF1860_01166 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | 0.546 |
| KXB77366.1 | KXB78458.1 | HMPREF1860_01423 | HMPREF1860_00960 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | KEGG: fna:OOM_0180 4.5e-30 IMP dehydrogenase/GMP reductase:von Willebrand factor, type A K07114; Psort location: CytoplasmicMembrane, score: 10.00. | 0.624 |
| KXB77366.1 | KXB78459.1 | HMPREF1860_01423 | HMPREF1860_00961 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | KEGG: fna:OOM_0180 1.2e-21 IMP dehydrogenase/GMP reductase:von Willebrand factor, type A K07114; Psort location: CytoplasmicMembrane, score: 9.99. | 0.624 |
| KXB77366.1 | KXB81327.1 | HMPREF1860_01423 | HMPREF1860_00227 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.520 |
| KXB77366.1 | glyA | HMPREF1860_01423 | HMPREF1860_00619 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.690 |
| KXB77366.1 | menG | HMPREF1860_01423 | HMPREF1860_00726 | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.612 |
| KXB77367.1 | KXB77366.1 | HMPREF1860_01424 | HMPREF1860_01423 | Hypothetical protein. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.548 |
| KXB77468.1 | KXB77366.1 | HMPREF1860_01365 | HMPREF1860_01423 | Prenyltransferase, UbiA family; KEGG: ctc:CTC01291 5.8e-46 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the UbiA prenyltransferase family. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.599 |
| KXB77468.1 | menG | HMPREF1860_01365 | HMPREF1860_00726 | Prenyltransferase, UbiA family; KEGG: ctc:CTC01291 5.8e-46 phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the UbiA prenyltransferase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.583 |
| KXB78123.1 | KXB77366.1 | HMPREF1860_01166 | HMPREF1860_01423 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.546 |
| KXB78458.1 | KXB77366.1 | HMPREF1860_00960 | HMPREF1860_01423 | KEGG: fna:OOM_0180 4.5e-30 IMP dehydrogenase/GMP reductase:von Willebrand factor, type A K07114; Psort location: CytoplasmicMembrane, score: 10.00. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.624 |
| KXB78458.1 | KXB78459.1 | HMPREF1860_00960 | HMPREF1860_00961 | KEGG: fna:OOM_0180 4.5e-30 IMP dehydrogenase/GMP reductase:von Willebrand factor, type A K07114; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: fna:OOM_0180 1.2e-21 IMP dehydrogenase/GMP reductase:von Willebrand factor, type A K07114; Psort location: CytoplasmicMembrane, score: 9.99. | 0.846 |
| KXB78459.1 | KXB77366.1 | HMPREF1860_00961 | HMPREF1860_01423 | KEGG: fna:OOM_0180 1.2e-21 IMP dehydrogenase/GMP reductase:von Willebrand factor, type A K07114; Psort location: CytoplasmicMembrane, score: 9.99. | Methyltransferase domain protein; KEGG: pel:SAR11G3_00145 2.4e-15 3-demethylubiquinone-9 3-methyltransferase K00568; Psort location: Cytoplasmic, score: 8.96. | 0.624 |