Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB77267.1Hypothetical protein. (137 aa)    
Predicted Functional Partners:
KXB77268.1
Hypothetical protein.
       0.775
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.731
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
 
 0.661
KXB79765.1
KEGG: cba:CLB_2447 2.1e-16 Clp protease; K01358 ATP-dependent Clp protease, protease subunit; Psort location: Cytoplasmic, score: 8.96; Belongs to the peptidase S14 family.
    
 
 0.633
clpP
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
    
 
 0.633
KXB77269.1
RteC protein; Psort location: Cytoplasmic, score: 8.96.
       0.593
KXB78228.1
KEGG: pit:PIN17_A1822 3.4e-144 ftcD; glutamate formimidoyltransferase; Psort location: Cytoplasmic, score: 8.96.
     
 0.578
KXB77264.1
Putative translation elongation factor G; KEGG: bnm:BALAC2494_01437 4.4e-64 Protein-synthesizing GTPase; Psort location: Cytoplasmic, score: 9.97.
     
 0.491
KXB77265.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: zga:zobellia_1342 6.0e-50 two-component system hybrid-sensor histidine kinase/response regulator, receiver domain; Psort location: CytoplasmicMembrane, score: 10.00.
       0.476
KXB77266.1
Sigma-54 interaction domain protein; KEGG: pfe:PSF113_0046 1.1e-65 algB; protein AlgB; Psort location: Cytoplasmic, score: 9.97.
       0.474
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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