STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB77267.1Hypothetical protein. (137 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.783
KXB77268.1
Hypothetical protein.
       0.779
KXB77269.1
RteC protein; Psort location: Cytoplasmic, score: 8.96.
       0.591
KXB78228.1
KEGG: pit:PIN17_A1822 3.4e-144 ftcD; glutamate formimidoyltransferase; Psort location: Cytoplasmic, score: 8.96.
     
 0.566
KXB77264.1
Putative translation elongation factor G; KEGG: bnm:BALAC2494_01437 4.4e-64 Protein-synthesizing GTPase; Psort location: Cytoplasmic, score: 9.97.
     
 0.492
tdk
Thymidine kinase; KEGG: pit:PIN17_A1240 7.7e-83 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.484
KXB77265.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: zga:zobellia_1342 6.0e-50 two-component system hybrid-sensor histidine kinase/response regulator, receiver domain; Psort location: CytoplasmicMembrane, score: 10.00.
       0.471
KXB77266.1
Sigma-54 interaction domain protein; KEGG: pfe:PSF113_0046 1.1e-65 algB; protein AlgB; Psort location: Cytoplasmic, score: 9.97.
       0.470
KXB81959.1
KEGG: pru:PRU_0197 4.8e-58 cytidine/deoxycytidylate deaminase zinc-binding domain-containing protein; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.469
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.465
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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