STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB77325.1KEGG: pmz:HMPREF0659_A5381 1.5e-72 hpt; hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)    
Predicted Functional Partners:
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
 
 
 0.992
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
 
 0.877
KXB74170.1
KEGG: pmz:HMPREF0659_A5845 1.5e-93 purine nucleoside phosphorylase I, inosine and guanosine-specific K03783; Psort location: Cytoplasmic, score: 8.96.
  
 0.875
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.841
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.815
KXB78292.1
Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
   
  0.774
KXB81943.1
Tetratricopeptide repeat domain protein; KEGG: ccm:Ccan_18230 2.0e-91 PIF1/RRM3 DNA helicase-like protein; Psort location: Cytoplasmic, score: 8.96.
    
  0.773
KXB79105.1
Peptidase family M49; KEGG: pmz:HMPREF0659_A6864 7.1e-238 peptidase, M49 family; K01277 dipeptidyl-peptidase III; Psort location: Cytoplasmic, score: 8.96.
    
  0.773
ftsH
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.760
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.757
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.