STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB76119.1ThiF family protein; KEGG: dai:Desaci_2489 2.7e-16 thiamine biosynthesis protein ThiF, family 2; K03148 sulfur carrier protein ThiS adenylyltransferase; Psort location: Cytoplasmic, score: 8.96. (266 aa)    
Predicted Functional Partners:
KXB79566.1
ThiF family protein; KEGG: bpb:bpr_I2644 8.2e-63 thiF; thiamine biosynthesis protein ThiF; Psort location: Cytoplasmic, score: 9.97.
 
0.622
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.610
KXB76120.1
Hypothetical protein; KEGG: vpo:Kpol_1013p52 0.00030 hypothetical protein; K15562 serine/threonine-protein kinase BUR1; Psort location: OuterMembrane, score: 9.49.
       0.594
alaS
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
    
  0.566
KXB77307.1
Thioredoxin-disulfide reductase; KEGG: pmz:HMPREF0659_A6627 2.7e-135 trxB; thioredoxin-disulfide reductase K00384; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.548
KXB75686.1
Hypothetical protein.
 
    0.508
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 
 0.507
KXB75066.1
Thiamine monophosphate synthase/TENI; KEGG: pit:PIN17_A0607 8.0e-49 putative thiamine-phosphate diphosphorylase; K00788 thiamine-phosphate pyrophosphorylase.
  
 
 0.507
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
 
 0.467
KXB75062.1
KEGG: pit:PIN17_A0611 1.1e-76 thiD; phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.422
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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