Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrBKEGG: pdn:HMPREF9137_2308 4.1e-148 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa)    
Predicted Functional Partners:
carA
KEGG: pmz:HMPREF0659_A5880 6.6e-180 carA; carbamoyl-phosphate synthase, small subunit K01956; Psort location: Cytoplasmic, score: 9.26; Belongs to the CarA family.
 
 0.999
KXB79153.1
Dihydroorotase; KEGG: pmz:HMPREF0659_A5999 3.6e-156 amidohydrolase family protein; K01465 dihydroorotase; Psort location: Cytoplasmic, score: 9.97.
 0.999
pyrI
Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase.
 0.999
KXB81939.1
KEGG: pdn:HMPREF9137_1362 0. carB; carbamoyl-phosphate synthase large subunit K01955; Psort location: Cytoplasmic, score: 9.97.
 
 0.997
KXB77786.1
ATP-grasp domain protein; KEGG: pmz:HMPREF0659_A5893 4.6e-101 ATP-grasp domain protein; K01955 carbamoyl-phosphate synthase large subunit; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.980
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.958
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.947
KXB77505.1
KEGG: bhl:Bache_2300 2.3e-83 dihydroorotate oxidase B, electron transfer subunit K02823; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.943
KXB79099.1
KEGG: pmz:HMPREF0659_A6727 4.3e-112 pyrF; orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.936
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.894
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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