Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speAArginine 2-monooxygenase; Catalyzes the biosynthesis of agmatine from arginine. (630 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.727
KXB78995.1
Hypothetical protein; KEGG: cyh:Cyan8802_1013 5.7e-87 Agmatine deiminase; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.725
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.712
KXB75710.1
Hypothetical protein.
       0.608
KXB75711.1
Sigma-70 region 2; KEGG: ccm:Ccan_05890 5.3e-20 putative RNA polymerase sigma factor rfaY K03088; Psort location: Cytoplasmic, score: 9.26; Belongs to the sigma-70 factor family. ECF subfamily.
       0.608
KXB75632.1
Hypothetical protein; KEGG: pmz:HMPREF0659_A5557 9.2e-32 lys1; saccharopine dehydrogenase K00290.
    
 0.594
KXB75578.1
KEGG: pdn:HMPREF9137_1758 8.3e-173 saccharopine dehydrogenase; Psort location: Cytoplasmic, score: 8.96.
    
 0.594
KXB75716.1
Hydrolase, NUDIX family; KEGG: pmz:HMPREF0659_A5133 9.3e-55 mutator MutT protein; Psort location: Cytoplasmic, score: 8.96.
       0.478
KXB77307.1
Thioredoxin-disulfide reductase; KEGG: pmz:HMPREF0659_A6627 2.7e-135 trxB; thioredoxin-disulfide reductase K00384; Psort location: Cytoplasmic, score: 9.97.
     
  0.420
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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