| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74394.1 | KXB79136.1 | HMPREF1860_02035 | HMPREF1860_00680 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | 0.708 |
| KXB74394.1 | dinB | HMPREF1860_02035 | HMPREF1860_00632 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.956 |
| KXB74394.1 | polA | HMPREF1860_02035 | HMPREF1860_00085 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
| KXB74394.1 | recA | HMPREF1860_02035 | HMPREF1860_01792 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.874 |
| KXB74394.1 | rnhB | HMPREF1860_02035 | HMPREF1860_01768 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.867 |
| KXB75724.1 | KXB75725.1 | HMPREF1860_01765 | HMPREF1860_01766 | FeS assembly ATPase SufC; KEGG: ccm:Ccan_19350 3.9e-79 putative ATP-dependent transporter sufC K09013; Psort location: Cytoplasmic, score: 9.97. | FeS assembly protein SufD; KEGG: apb:SAR116_0016 2.3e-24 Fe-S center production/stability protein SufD K09015; Psort location: Cytoplasmic, score: 8.96. | 0.996 |
| KXB75724.1 | KXB75726.1 | HMPREF1860_01765 | HMPREF1860_01767 | FeS assembly ATPase SufC; KEGG: ccm:Ccan_19350 3.9e-79 putative ATP-dependent transporter sufC K09013; Psort location: Cytoplasmic, score: 9.97. | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.995 |
| KXB75724.1 | rnhB | HMPREF1860_01765 | HMPREF1860_01768 | FeS assembly ATPase SufC; KEGG: ccm:Ccan_19350 3.9e-79 putative ATP-dependent transporter sufC K09013; Psort location: Cytoplasmic, score: 9.97. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.770 |
| KXB75725.1 | KXB75724.1 | HMPREF1860_01766 | HMPREF1860_01765 | FeS assembly protein SufD; KEGG: apb:SAR116_0016 2.3e-24 Fe-S center production/stability protein SufD K09015; Psort location: Cytoplasmic, score: 8.96. | FeS assembly ATPase SufC; KEGG: ccm:Ccan_19350 3.9e-79 putative ATP-dependent transporter sufC K09013; Psort location: Cytoplasmic, score: 9.97. | 0.996 |
| KXB75725.1 | KXB75726.1 | HMPREF1860_01766 | HMPREF1860_01767 | FeS assembly protein SufD; KEGG: apb:SAR116_0016 2.3e-24 Fe-S center production/stability protein SufD K09015; Psort location: Cytoplasmic, score: 8.96. | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | 0.986 |
| KXB75725.1 | rnhB | HMPREF1860_01766 | HMPREF1860_01768 | FeS assembly protein SufD; KEGG: apb:SAR116_0016 2.3e-24 Fe-S center production/stability protein SufD K09015; Psort location: Cytoplasmic, score: 8.96. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.770 |
| KXB75726.1 | KXB75724.1 | HMPREF1860_01767 | HMPREF1860_01765 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | FeS assembly ATPase SufC; KEGG: ccm:Ccan_19350 3.9e-79 putative ATP-dependent transporter sufC K09013; Psort location: Cytoplasmic, score: 9.97. | 0.995 |
| KXB75726.1 | KXB75725.1 | HMPREF1860_01767 | HMPREF1860_01766 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | FeS assembly protein SufD; KEGG: apb:SAR116_0016 2.3e-24 Fe-S center production/stability protein SufD K09015; Psort location: Cytoplasmic, score: 8.96. | 0.986 |
| KXB75726.1 | rnhB | HMPREF1860_01767 | HMPREF1860_01768 | Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.797 |
| KXB79136.1 | KXB74394.1 | HMPREF1860_00680 | HMPREF1860_02035 | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.708 |
| KXB79136.1 | polA | HMPREF1860_00680 | HMPREF1860_00085 | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.886 |
| KXB79136.1 | recA | HMPREF1860_00680 | HMPREF1860_01792 | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.793 |
| KXB79136.1 | rnhB | HMPREF1860_00680 | HMPREF1860_01768 | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.722 |
| KXB79145.1 | rnhB | HMPREF1860_00689 | HMPREF1860_01768 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.759 |
| dinB | KXB74394.1 | HMPREF1860_00632 | HMPREF1860_02035 | Putative DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.956 |