| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74394.1 | KXB75158.1 | HMPREF1860_02035 | HMPREF1860_01835 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | 0.708 |
| KXB74394.1 | KXB75728.1 | HMPREF1860_02035 | HMPREF1860_01769 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6764 0. putative ATP-dependent helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.26. | 0.781 |
| KXB74394.1 | KXB79112.1 | HMPREF1860_02035 | HMPREF1860_00656 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 7.4e-291 UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | 0.965 |
| KXB74394.1 | KXB79136.1 | HMPREF1860_02035 | HMPREF1860_00680 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | 0.708 |
| KXB74394.1 | KXB79708.1 | HMPREF1860_02035 | HMPREF1860_00553 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; KEGG: nth:Nther_0809 3.3e-09 LexA repressor; Psort location: Cytoplasmic, score: 8.96. | 0.448 |
| KXB74394.1 | KXB81943.1 | HMPREF1860_02035 | HMPREF1860_00037 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Tetratricopeptide repeat domain protein; KEGG: ccm:Ccan_18230 2.0e-91 PIF1/RRM3 DNA helicase-like protein; Psort location: Cytoplasmic, score: 8.96. | 0.708 |
| KXB74394.1 | mutL | HMPREF1860_02035 | HMPREF1860_01777 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.922 |
| KXB74394.1 | polA | HMPREF1860_02035 | HMPREF1860_00085 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
| KXB74394.1 | topA | HMPREF1860_02035 | HMPREF1860_01755 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.423 |
| KXB75158.1 | KXB74394.1 | HMPREF1860_01835 | HMPREF1860_02035 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.708 |
| KXB75158.1 | KXB75728.1 | HMPREF1860_01835 | HMPREF1860_01769 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6764 0. putative ATP-dependent helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.26. | 0.765 |
| KXB75158.1 | KXB79112.1 | HMPREF1860_01835 | HMPREF1860_00656 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6530 7.4e-291 UvrD/REP helicase K03657; Psort location: Cytoplasmic, score: 9.97. | 0.906 |
| KXB75158.1 | KXB79136.1 | HMPREF1860_01835 | HMPREF1860_00680 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | 0.940 |
| KXB75158.1 | KXB79708.1 | HMPREF1860_01835 | HMPREF1860_00553 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: nth:Nther_0809 3.3e-09 LexA repressor; Psort location: Cytoplasmic, score: 8.96. | 0.566 |
| KXB75158.1 | KXB81943.1 | HMPREF1860_01835 | HMPREF1860_00037 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | Tetratricopeptide repeat domain protein; KEGG: ccm:Ccan_18230 2.0e-91 PIF1/RRM3 DNA helicase-like protein; Psort location: Cytoplasmic, score: 8.96. | 0.754 |
| KXB75158.1 | mutL | HMPREF1860_01835 | HMPREF1860_01777 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.717 |
| KXB75158.1 | polA | HMPREF1860_01835 | HMPREF1860_00085 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.886 |
| KXB75158.1 | topA | HMPREF1860_01835 | HMPREF1860_01755 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.751 |
| KXB75728.1 | KXB74394.1 | HMPREF1860_01769 | HMPREF1860_02035 | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6764 0. putative ATP-dependent helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.26. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.781 |
| KXB75728.1 | KXB75158.1 | HMPREF1860_01769 | HMPREF1860_01835 | UvrD/REP helicase; KEGG: pmz:HMPREF0659_A6764 0. putative ATP-dependent helicase PcrA; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.26. | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | 0.765 |
