STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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[Homology]
Score
thiCThiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (523 aa)    
Predicted Functional Partners:
KXB75062.1
KEGG: pit:PIN17_A0611 1.1e-76 thiD; phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.988
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
 
 0.971
KXB75066.1
Thiamine monophosphate synthase/TENI; KEGG: pit:PIN17_A0607 8.0e-49 putative thiamine-phosphate diphosphorylase; K00788 thiamine-phosphate pyrophosphorylase.
 
 
 0.913
KXB74489.1
KEGG: bhl:Bache_2367 8.7e-36 phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 9.26.
  
 
 0.862
thi4
Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
  
  
 0.677
KXB81586.1
Hypothetical protein; KEGG: cby:CLM_0574 0.00014 bacteriocin biosynthesis cyclodehydratase; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.610
KXB76119.1
ThiF family protein; KEGG: dai:Desaci_2489 2.7e-16 thiamine biosynthesis protein ThiF, family 2; K03148 sulfur carrier protein ThiS adenylyltransferase; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.610
KXB79097.1
Hypothetical protein; KEGG: pmz:HMPREF0659_A6730 2.4e-182 hypothetical protein; K01933 phosphoribosylformylglycinamidine cyclo-ligase; Psort location: Cytoplasmic, score: 9.97.
     
 0.580
purC
KEGG: pmz:HMPREF0659_A6716 1.9e-150 purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923; Psort location: Cytoplasmic, score: 8.96; Belongs to the SAICAR synthetase family.
    
 0.536
KXB78968.1
Putative pyridoxal kinase; KEGG: pmz:HMPREF0659_A6314 7.6e-115 phosphomethylpyrimidine kinase K00868; Psort location: Cytoplasmic, score: 8.96.
     
  0.499
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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