| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74966.1 | gyrB | HMPREF1860_01931 | HMPREF1860_01927 | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.777 |
| KXB75028.1 | gyrB | HMPREF1860_01911 | HMPREF1860_01927 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.777 |
| KXB75158.1 | KXB79136.1 | HMPREF1860_01835 | HMPREF1860_00680 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | 0.940 |
| KXB75158.1 | gyrB | HMPREF1860_01835 | HMPREF1860_01927 | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.656 |
| KXB75442.1 | gyrB | HMPREF1860_01825 | HMPREF1860_01927 | Transposase, IS4 family; KEGG: efc:EFAU004_01897 0.0036 IS1380 family transposase; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.776 |
| KXB76235.1 | gyrA | HMPREF1860_01635 | HMPREF1860_02049 | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.628 |
| KXB76235.1 | gyrB | HMPREF1860_01635 | HMPREF1860_01927 | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.917 |
| KXB76963.1 | gyrB | HMPREF1860_01529 | HMPREF1860_01927 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.777 |
| KXB77397.1 | gyrB | HMPREF1860_01417 | HMPREF1860_01927 | Hypothetical protein; KEGG: efc:EFAU004_01897 0.00078 IS1380 family transposase; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.776 |
| KXB79136.1 | KXB75158.1 | HMPREF1860_00680 | HMPREF1860_01835 | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | 0.940 |
| KXB79136.1 | gyrB | HMPREF1860_00680 | HMPREF1860_01927 | KEGG: pmz:HMPREF0659_A5961 1.6e-242 ATP-dependent DNA helicase, RecQ family K03654; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.656 |
| gyrA | KXB76235.1 | HMPREF1860_02049 | HMPREF1860_01635 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | 0.628 |
| gyrA | gyrB | HMPREF1860_02049 | HMPREF1860_01927 | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.971 |
| gyrB | KXB74966.1 | HMPREF1860_01927 | HMPREF1860_01931 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82. | 0.777 |
| gyrB | KXB75028.1 | HMPREF1860_01927 | HMPREF1860_01911 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.777 |
| gyrB | KXB75158.1 | HMPREF1860_01927 | HMPREF1860_01835 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | KEGG: pmz:HMPREF0659_A6179 0. recQ; ATP-dependent DNA helicase RecQ K03654; Psort location: Cytoplasmic, score: 9.97. | 0.656 |
| gyrB | KXB75442.1 | HMPREF1860_01927 | HMPREF1860_01825 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Transposase, IS4 family; KEGG: efc:EFAU004_01897 0.0036 IS1380 family transposase; Psort location: Cytoplasmic, score: 8.96. | 0.776 |
| gyrB | KXB76235.1 | HMPREF1860_01927 | HMPREF1860_01635 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | 0.917 |
| gyrB | KXB76963.1 | HMPREF1860_01927 | HMPREF1860_01529 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.777 |
| gyrB | KXB77397.1 | HMPREF1860_01927 | HMPREF1860_01417 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Hypothetical protein; KEGG: efc:EFAU004_01897 0.00078 IS1380 family transposase; Psort location: Cytoplasmic, score: 8.96. | 0.776 |
