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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxSPyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (291 aa)    
Predicted Functional Partners:
pdxT
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.999
KXB74489.1
KEGG: bhl:Bache_2367 8.7e-36 phosphomethylpyrimidine kinase K00941; Psort location: Cytoplasmic, score: 9.26.
    
 0.827
KXB78009.1
KEGG: pit:PIN17_A1294 9.4e-165 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.822
KXB78968.1
Putative pyridoxal kinase; KEGG: pmz:HMPREF0659_A6314 7.6e-115 phosphomethylpyrimidine kinase K00868; Psort location: Cytoplasmic, score: 8.96.
   
 0.675
KXB79500.1
Transketolase, thiamine diphosphate binding domain protein; KEGG: pmz:HMPREF0659_A6472 4.0e-299 putative transketolase; K00615 transketolase; Psort location: Cytoplasmic, score: 9.26; Belongs to the transketolase family.
   
 
  0.651
KXB81950.1
KEGG: pmz:HMPREF0659_A6685 5.6e-151 prs; ribose-phosphate diphosphokinase K00948; Psort location: Cytoplasmic, score: 9.26.
   
 
  0.638
KXB81981.1
KEGG: dtu:Dtur_0663 9.8e-18 LacI family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97.
    
  0.583
KXB75624.1
Transcriptional regulator, LacI family; KEGG: fjo:Fjoh_1259 5.9e-53 alanine racemase K01775; Psort location: Cytoplasmic, score: 9.97.
    
  0.583
KXB80412.1
Kinase, PfkB family; KEGG: pmz:HMPREF0659_A5106 2.0e-116 kinase, PfkB family; K00847 fructokinase; Psort location: Cytoplasmic, score: 8.96.
     
 0.495
nnrD
YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
 
 0.477
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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