| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74319.1 | KXB74321.1 | HMPREF1860_02050 | HMPREF1860_02052 | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.724 |
| KXB74319.1 | KXB74322.1 | HMPREF1860_02050 | HMPREF1860_02053 | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | 0.614 |
| KXB74319.1 | gyrA | HMPREF1860_02050 | HMPREF1860_02049 | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.770 |
| KXB74321.1 | KXB74319.1 | HMPREF1860_02052 | HMPREF1860_02050 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | 0.724 |
| KXB74321.1 | KXB74322.1 | HMPREF1860_02052 | HMPREF1860_02053 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | 0.849 |
| KXB74321.1 | gyrA | HMPREF1860_02052 | HMPREF1860_02049 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.578 |
| KXB74322.1 | KXB74319.1 | HMPREF1860_02053 | HMPREF1860_02050 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | 0.614 |
| KXB74322.1 | KXB74321.1 | HMPREF1860_02053 | HMPREF1860_02052 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.849 |
| KXB74322.1 | gyrA | HMPREF1860_02053 | HMPREF1860_02049 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.595 |
| KXB78158.1 | gyrA | HMPREF1860_01201 | HMPREF1860_02049 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.824 |
| KXB78158.1 | metG | HMPREF1860_01201 | HMPREF1860_02012 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.463 |
| KXB78972.1 | gyrA | HMPREF1860_00812 | HMPREF1860_02049 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.939 |
| KXB78972.1 | metG | HMPREF1860_00812 | HMPREF1860_02012 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.463 |
| dnaK | ftsZ | HMPREF1860_01307 | HMPREF1860_01350 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.443 |
| dnaK | gyrA | HMPREF1860_01307 | HMPREF1860_02049 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.546 |
| dnaK | gyrB | HMPREF1860_01307 | HMPREF1860_01927 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.423 |
| dnaK | metG | HMPREF1860_01307 | HMPREF1860_02012 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.441 |
| ftsZ | dnaK | HMPREF1860_01350 | HMPREF1860_01307 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.443 |
| ftsZ | gyrA | HMPREF1860_01350 | HMPREF1860_02049 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.557 |
| ftsZ | gyrB | HMPREF1860_01350 | HMPREF1860_01927 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.467 |