| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74319.1 | KXB74322.1 | HMPREF1860_02050 | HMPREF1860_02053 | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | 0.545 |
| KXB74319.1 | gyrA | HMPREF1860_02050 | HMPREF1860_02049 | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.727 |
| KXB74322.1 | KXB74319.1 | HMPREF1860_02053 | HMPREF1860_02050 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: sgn:SGRA_3959 0.00020 glycosyl transferase family protein; Psort location: Periplasmic, score: 9.84. | 0.545 |
| KXB74322.1 | dnaK | HMPREF1860_02053 | HMPREF1860_01307 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.653 |
| KXB74322.1 | gyrA | HMPREF1860_02053 | HMPREF1860_02049 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.527 |
| KXB74322.1 | rpoA | HMPREF1860_02053 | HMPREF1860_00214 | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.493 |
| KXB76235.1 | KXB78158.1 | HMPREF1860_01635 | HMPREF1860_01201 | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.775 |
| KXB76235.1 | KXB78972.1 | HMPREF1860_01635 | HMPREF1860_00812 | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. | 0.967 |
| KXB76235.1 | gyrA | HMPREF1860_01635 | HMPREF1860_02049 | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.628 |
| KXB76235.1 | gyrB | HMPREF1860_01635 | HMPREF1860_01927 | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.917 |
| KXB78158.1 | KXB76235.1 | HMPREF1860_01201 | HMPREF1860_01635 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | 0.775 |
| KXB78158.1 | gyrA | HMPREF1860_01201 | HMPREF1860_02049 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.775 |
| KXB78972.1 | KXB76235.1 | HMPREF1860_00812 | HMPREF1860_01635 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. | KEGG: pmz:HMPREF0659_A6144 0. DNA gyrase/topoisomerase IV, A subunit; K02621 topoisomerase IV subunit A; Psort location: Cytoplasmic, score: 9.97. | 0.967 |
| KXB78972.1 | gyrA | HMPREF1860_00812 | HMPREF1860_02049 | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pmz:HMPREF0659_A5055 0. DNA topoisomerase IV subunit B; K02622 topoisomerase IV subunit B; Psort location: Cytoplasmic, score: 9.97. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.940 |
| dnaK | KXB74322.1 | HMPREF1860_01307 | HMPREF1860_02053 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97. | 0.653 |
| dnaK | gyrA | HMPREF1860_01307 | HMPREF1860_02049 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.604 |
| dnaK | gyrB | HMPREF1860_01307 | HMPREF1860_01927 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.599 |
| dnaK | recA | HMPREF1860_01307 | HMPREF1860_01792 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.491 |
| dnaK | rpoA | HMPREF1860_01307 | HMPREF1860_00214 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.657 |
| dnaK | tuf | HMPREF1860_01307 | HMPREF1860_01718 | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. | 0.548 |
