STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serCPutative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (375 aa)    
Predicted Functional Partners:
KXB74324.1
D-phosphoglycerate dehydrogenase; KEGG: pit:PIN17_A1251 6.5e-125 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain protein; K00058 D-3-phosphoglycerate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 
 0.994
KXB79015.1
KEGG: pmz:HMPREF0659_A5946 3.7e-131 pdxA; pyridoxal phosphate biosynthetic protein PdxA; K00097 4-hydroxythreonine-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
     
 0.843
KXB78750.1
Cysteine synthase A; KEGG: pmz:HMPREF0659_A6111 6.0e-131 cysK; cysteine synthase A K01738; Psort location: Cytoplasmic, score: 9.26; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.687
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
    
 0.675
KXB77467.1
HAD hydrolase, family IB; KEGG: tdn:Suden_1221 2.3e-28 phosphoserine phosphatase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.672
aroA
Putative 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
  
 0.671
KXB74322.1
KEGG: phe:Phep_1011 6.7e-84 DEAD/DEAH box helicase; K05591 ATP-independent RNA helicase DbpA; Psort location: Cytoplasmic, score: 9.97.
       0.669
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.662
KXB79166.1
KEGG: pdn:HMPREF9137_1471 1.2e-157 putative 3-deoxy-7-phosphoheptulonate synthase; K04516 chorismate mutase; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.649
KXB74325.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
       0.599
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.