STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated endonuclease Cas1, NMENI subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (311 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
cas9
CRISPR-associated protein, Csn1 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this [...]
 
   
 0.972
KXB78453.1
DNA-binding protein HU; KEGG: apb:SAR116_0173 1.3e-09 integration host factor subunit alpha K04764; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial histone-like protein family.
    
   0.533
KXB78454.1
DNA-binding protein HU; KEGG: phu:Phum_PHUM249060 0.00012 hypothetical protein; K14437 chromodomain-helicase-DNA-binding protein 7; Psort location: Cytoplasmic, score: 8.96; Belongs to the bacterial histone-like protein family.
    
   0.533
KXB78258.1
DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.533
KXB77722.1
Putative DNA-binding protein.
    
   0.533
KXB77621.1
Putative DNA-binding protein.
    
   0.533
KXB74107.1
DNA-binding protein HU; KEGG: apb:SAR116_0125 1.5e-08 histone family protein DNA-binding protein K03530; Belongs to the bacterial histone-like protein family.
    
   0.533
KXB76534.1
Putative DNA-binding protein.
    
   0.504
KXB78793.1
KEGG: pmz:HMPREF0659_A5655 2.0e-139 putative arabinose 5-phosphate isomerase; K06041 arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily.
    
   0.487
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.