STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB74107.1DNA-binding protein HU; KEGG: apb:SAR116_0125 1.5e-08 histone family protein DNA-binding protein K03530; Belongs to the bacterial histone-like protein family. (92 aa)    
Predicted Functional Partners:
KXB74108.1
KEGG: pdn:HMPREF9137_0196 6.5e-118 putative pantothenate kinase; K09680 type II pantothenate kinase; Psort location: CytoplasmicMembrane, score: 9.82.
       0.678
KXB74106.1
KEGG: pdn:HMPREF9137_0198 5.9e-250 S1 RNA binding domain-containing protein; K08301 ribonuclease G; Psort location: Cytoplasmic, score: 9.97.
     
 0.640
cas1
CRISPR-associated endonuclease Cas1, NMENI subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
    
   0.533
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.471
cas2
CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
    
   0.456
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.445
KXB81981.1
KEGG: dtu:Dtur_0663 9.8e-18 LacI family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.442
KXB75624.1
Transcriptional regulator, LacI family; KEGG: fjo:Fjoh_1259 5.9e-53 alanine racemase K01775; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.442
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
  
 0.426
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
   0.425
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.