Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KXB74143.1Haloacid dehalogenase-like hydrolase; KEGG: zga:zobellia_482 1.1e-42 nanP; N-acylneuraminate-9-phosphatase K07025; Psort location: Cytoplasmic, score: 8.96. (234 aa)    
Predicted Functional Partners:
KXB81394.1
KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97.
    
 0.872
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.871
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
 0.815
KXB74144.1
ATP-binding protein, Mrp/Nbp35 family; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.594
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.532
KXB78942.1
KEGG: pdn:HMPREF9137_0478 9.9e-106 uracil phosphoribosyltransferase K00761; Psort location: Cytoplasmic, score: 9.97.
 
  
  0.529
KXB79169.1
KEGG: pmz:HMPREF0659_A7207 5.4e-82 ribF; riboflavin biosynthesis protein RibF K11753; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.513
KXB76006.1
HAD hydrolase, family IA, variant 3; KEGG: pmz:HMPREF0659_A6736 2.1e-87 putative phosphoglycolate phosphatase, bacterial; K01091 phosphoglycolate phosphatase; Psort location: Cytoplasmic, score: 9.97.
    
 0.510
KXB74170.1
KEGG: pmz:HMPREF0659_A5845 1.5e-93 purine nucleoside phosphorylase I, inosine and guanosine-specific K03783; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.507
serC
Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
   
 
 0.504
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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