| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXB74153.1 | ribBA | HMPREF1860_02143 | HMPREF1860_02144 | Permease, YjgP/YjgQ family; KEGG: hiq:CGSHiGG_02270 0.0013 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K07091; Psort location: CytoplasmicMembrane, score: 10.00. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.799 |
| KXB74999.1 | KXB78292.1 | HMPREF1860_01918 | HMPREF1860_00993 | Tetratricopeptide repeat protein; KEGG: tet:TTHERM_00391570 4.6e-12 DNA polymerase family B containing protein K02350; Psort location: Cytoplasmic, score: 8.96. | Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.662 |
| KXB74999.1 | KXB80103.1 | HMPREF1860_01918 | HMPREF1860_00389 | Tetratricopeptide repeat protein; KEGG: tet:TTHERM_00391570 4.6e-12 DNA polymerase family B containing protein K02350; Psort location: Cytoplasmic, score: 8.96. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.00066 TPR repeat-containing serine/threonine protein kinase K00908. | 0.586 |
| KXB74999.1 | ribBA | HMPREF1860_01918 | HMPREF1860_02144 | Tetratricopeptide repeat protein; KEGG: tet:TTHERM_00391570 4.6e-12 DNA polymerase family B containing protein K02350; Psort location: Cytoplasmic, score: 8.96. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.885 |
| KXB75997.1 | KXB81388.1 | HMPREF1860_01666 | HMPREF1860_00162 | Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.9e-07 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 8.96. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.602 |
| KXB75997.1 | ribBA | HMPREF1860_01666 | HMPREF1860_02144 | Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.9e-07 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 8.96. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.888 |
| KXB78292.1 | KXB74999.1 | HMPREF1860_00993 | HMPREF1860_01918 | Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Tetratricopeptide repeat protein; KEGG: tet:TTHERM_00391570 4.6e-12 DNA polymerase family B containing protein K02350; Psort location: Cytoplasmic, score: 8.96. | 0.662 |
| KXB78292.1 | KXB80103.1 | HMPREF1860_00993 | HMPREF1860_00389 | Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.00066 TPR repeat-containing serine/threonine protein kinase K00908. | 0.720 |
| KXB78292.1 | guaB | HMPREF1860_00993 | HMPREF1860_01772 | Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.676 |
| KXB78292.1 | ribBA | HMPREF1860_00993 | HMPREF1860_02144 | Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.898 |
| KXB78765.1 | KXB81394.1 | HMPREF1860_00895 | HMPREF1860_00168 | KEGG: pmz:HMPREF0659_A6707 7.9e-81 ribE; riboflavin synthase, alpha subunit K00793; Psort location: Cytoplasmic, score: 9.97. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| KXB78765.1 | ribBA | HMPREF1860_00895 | HMPREF1860_02144 | KEGG: pmz:HMPREF0659_A6707 7.9e-81 ribE; riboflavin synthase, alpha subunit K00793; Psort location: Cytoplasmic, score: 9.97. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| KXB78765.1 | ribH | HMPREF1860_00895 | HMPREF1860_00734 | KEGG: pmz:HMPREF0659_A6707 7.9e-81 ribE; riboflavin synthase, alpha subunit K00793; Psort location: Cytoplasmic, score: 9.97. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.997 |
| KXB80103.1 | KXB74999.1 | HMPREF1860_00389 | HMPREF1860_01918 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.00066 TPR repeat-containing serine/threonine protein kinase K00908. | Tetratricopeptide repeat protein; KEGG: tet:TTHERM_00391570 4.6e-12 DNA polymerase family B containing protein K02350; Psort location: Cytoplasmic, score: 8.96. | 0.586 |
| KXB80103.1 | KXB78292.1 | HMPREF1860_00389 | HMPREF1860_00993 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.00066 TPR repeat-containing serine/threonine protein kinase K00908. | Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96. | 0.720 |
| KXB80103.1 | ribBA | HMPREF1860_00389 | HMPREF1860_02144 | Tetratricopeptide repeat protein; KEGG: ava:Ava_1552 0.00066 TPR repeat-containing serine/threonine protein kinase K00908. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.885 |
| KXB81388.1 | KXB75997.1 | HMPREF1860_00162 | HMPREF1860_01666 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.9e-07 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 8.96. | 0.602 |
| KXB81388.1 | KXB81394.1 | HMPREF1860_00162 | HMPREF1860_00168 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97. | 0.565 |
| KXB81388.1 | guaB | HMPREF1860_00162 | HMPREF1860_01772 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.447 |
| KXB81388.1 | ribBA | HMPREF1860_00162 | HMPREF1860_02144 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.912 |