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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdkThymidine kinase; KEGG: pit:PIN17_A1240 7.7e-83 tdk; thymidine kinase K00857; Psort location: Cytoplasmic, score: 9.97. (196 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.930
dut
dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
 
 0.875
KXB78956.1
KEGG: pmz:HMPREF0659_A6360 5.0e-63 putative cytidine deaminase; K01489 cytidine deaminase.
    
 0.851
KXB74163.1
Hypothetical protein; KEGG: cfu:CFU_3842 2.4e-31 perM; putative permease; Psort location: CytoplasmicMembrane, score: 10.00.
       0.821
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
  
 0.755
KXB81959.1
KEGG: pru:PRU_0197 4.8e-58 cytidine/deoxycytidylate deaminase zinc-binding domain-containing protein; K01493 dCMP deaminase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.735
KXB74996.1
KEGG: pmz:HMPREF0659_A6645 3.1e-125 phosphorylase family protein; K00757 uridine phosphorylase; Psort location: Cytoplasmic, score: 9.97.
     
 0.694
rsmI
S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.685
surE
SurE-like protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
  
  0.677
KXB74170.1
KEGG: pmz:HMPREF0659_A5845 1.5e-93 purine nucleoside phosphorylase I, inosine and guanosine-specific K03783; Psort location: Cytoplasmic, score: 8.96.
    
  0.661
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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