Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (315 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 
 0.998
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
 0.997
cmk
Cytidylate kinase; KEGG: pmz:HMPREF0659_A7170 4.4e-87 cmk; cytidylate kinase K00945; Psort location: Cytoplasmic, score: 9.97.
   
  0.941
KXB74392.1
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
  
 0.910
KXB74108.1
KEGG: pdn:HMPREF9137_0196 6.5e-118 putative pantothenate kinase; K09680 type II pantothenate kinase; Psort location: CytoplasmicMembrane, score: 9.82.
     
 0.855
KXB78555.1
Hypothetical protein; KEGG: ccm:Ccan_10160 1.0e-39 putative Pyrroline-5-carboxylate reductase; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.697
KXB74185.1
KEGG: pmz:HMPREF0659_A6886 1.1e-106 starch synthase catalytic domain protein; K00703 starch synthase.
  
    0.668
KXB74186.1
Hypothetical protein.
       0.630
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.621
KXB74206.1
KEGG: pmz:HMPREF0659_A5436 5.1e-86 biotin--[acetyl-CoA-carboxylase] ligase K03524; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.618
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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