Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
folEKEGG: pit:PIN17_A1905 1.7e-87 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 9.97. (195 aa)    
Predicted Functional Partners:
KXB77819.1
Dihydropteroate synthase; KEGG: pdn:HMPREF9137_0315 1.5e-102 folP; dihydropteroate synthase K00796; Psort location: Cytoplasmic, score: 9.97.
 
 0.989
KXB79142.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.966
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
 
 0.906
KXB81394.1
KEGG: pit:PIN17_A0657 5.5e-105 ribD; riboflavin biosynthesis protein RibD K11752; Psort location: Cytoplasmic, score: 9.97.
    
 0.844
KXB80105.1
KEGG: pmz:HMPREF0659_A5634 0. nrdD; anaerobic ribonucleoside-triphosphate reductase K00527; Psort location: Cytoplasmic, score: 9.97.
     
  0.841
KXB79150.1
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.841
KXB79008.1
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.841
KXB75589.1
Adenylate cyclase; KEGG: pru:PRU_2493 7.4e-46 adenylate cyclase; Psort location: Cytoplasmic, score: 8.96.
     
  0.841
KXB79945.1
KEGG: pmz:HMPREF0659_A5483 4.5e-39 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase K00950; Psort location: Cytoplasmic, score: 9.26.
 
  
 0.837
KXB75997.1
Dinuclear metal center protein, YbgI family; KEGG: hip:CGSHiEE_02770 1.9e-07 seryl-tRNA synthetase; Psort location: Cytoplasmic, score: 8.96.
    
 0.831
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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