STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXB74245.1DnaJ domain protein; KEGG: tgo:TGME49_017710 0.0041 DnaJ domain-containing protein; Psort location: CytoplasmicMembrane, score: 9.99. (278 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.988
KXB80838.1
Hsp90 protein; KEGG: eab:ECABU_c05560 3.7e-67 htpG; heat shock protein HtpG K04079; Psort location: Cytoplasmic, score: 9.97.
  
 0.980
KXB78030.1
Pyruvate synthase; KEGG: pdn:HMPREF9137_1524 0. nifJ; pyruvate synthase K03737; Psort location: Cytoplasmic, score: 8.96.
   
 
 0.915
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
 
 
 0.903
KXB78292.1
Tetratricopeptide repeat protein; KEGG: apb:SAR116_1534 1.5e-05 hypothetical protein; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.889
KXB81943.1
Tetratricopeptide repeat domain protein; KEGG: ccm:Ccan_18230 2.0e-91 PIF1/RRM3 DNA helicase-like protein; Psort location: Cytoplasmic, score: 8.96.
   
 0.822
KXB79105.1
Peptidase family M49; KEGG: pmz:HMPREF0659_A6864 7.1e-238 peptidase, M49 family; K01277 dipeptidyl-peptidase III; Psort location: Cytoplasmic, score: 8.96.
   
 0.788
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
   
 
 0.770
KXB78068.1
KEGG: pfe:PSF113_2023 1.0e-09 MerR family transcriptional regulator.
  
 
 0.768
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.761
Your Current Organism:
Prevotella amnii
NCBI taxonomy Id: 419005
Other names: CCUG 53648, DSM 23384, JCM 14753, P. amnii, Prevotella amnii Lawson et al. 2008 emend. Hahnke et al. 2016
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.