STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
htpXPeptidase, M48 family; KEGG: blj:BLD_1349 5.9e-76 htpX; heat shock protein HtpX; K03799 heat shock protein HtpX; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the peptidase M48B family. (220 aa)    
Predicted Functional Partners:
KWZ72261.1
Hypothetical protein; KEGG: bbv:HMPREF9228_0092 2.9e-19 peptidase, M48 family K03799; Psort location: CytoplasmicMembrane, score: 9.55.
 
      0.736
KWZ74070.1
MaoC-like protein; KEGG: bad:BAD_0256 0. fas; fatty acid synthase Fas; K11533 fatty acid synthase, bacteria type; Psort location: CytoplasmicMembrane, score: 9.78.
   
 
 0.502
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.491
ftsH
ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 
 0.478
KWZ75696.1
DnaJ domain protein; KEGG: apb:SAR116_1614 9.0e-41 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.453
dnaJ
Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
  
 
 0.453
KWZ75676.1
Metal ion transporter, metal ion transporter family; KEGG: hiq:CGSHiGG_02375 7.3e-11 argininosuccinate synthase; Psort location: CytoplasmicMembrane, score: 10.00.
       0.447
KWZ75677.1
Putative magnesium transporter; KEGG: pmt:PMT0126 2.0e-36 Mg2+ transporter K06213; Psort location: CytoplasmicMembrane, score: 10.00.
       0.447
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
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