STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75544.1KEGG: lca:LSEI_1785 5.1e-118 3-hydroxy-3-methylglutaryl CoA synthase; K01641 hydroxymethylglutaryl-CoA synthase; Psort location: Cytoplasmic, score: 7.50. (397 aa)    
Predicted Functional Partners:
KWZ75545.1
KEGG: gvh:HMPREF9231_0431 5.3e-91 hydroxymethylglutaryl-CoA reductase, degradative K00054; Psort location: Cytoplasmic, score: 7.50; Belongs to the HMG-CoA reductase family.
 
 0.998
KWZ75546.1
KEGG: gvh:HMPREF9231_0432 2.6e-130 acetyl-CoA C-acetyltransferase; K00626 acetyl-CoA C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.997
KWZ74070.1
MaoC-like protein; KEGG: bad:BAD_0256 0. fas; fatty acid synthase Fas; K11533 fatty acid synthase, bacteria type; Psort location: CytoplasmicMembrane, score: 9.78.
  
 0.958
KWZ75985.1
Diphosphomevalonate decarboxylase; KEGG: sst:SSUST3_0299 4.1e-84 mvaD; mevalonate diphosphate decarboxylase; K01597 diphosphomevalonate decarboxylase.
 
 
 0.925
KWZ75986.1
KEGG: ssf:SSUA7_0272 3.1e-47 mevalonate kinase; K00938 phosphomevalonate kinase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.897
KWZ75984.1
Mevalonate kinase; KEGG: lre:Lreu_0915 6.1e-58 mevalonate kinase; K00869 mevalonate kinase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.896
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.881
KWZ72657.1
Citrate synthase 2; KEGG: sgt:SGGB_0689 7.6e-163 citZ; citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
    
 0.682
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
 0.660
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.645
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.