STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75545.1KEGG: gvh:HMPREF9231_0431 5.3e-91 hydroxymethylglutaryl-CoA reductase, degradative K00054; Psort location: Cytoplasmic, score: 7.50; Belongs to the HMG-CoA reductase family. (432 aa)    
Predicted Functional Partners:
KWZ75544.1
KEGG: lca:LSEI_1785 5.1e-118 3-hydroxy-3-methylglutaryl CoA synthase; K01641 hydroxymethylglutaryl-CoA synthase; Psort location: Cytoplasmic, score: 7.50.
 
 0.998
KWZ75984.1
Mevalonate kinase; KEGG: lre:Lreu_0915 6.1e-58 mevalonate kinase; K00869 mevalonate kinase; Psort location: Cytoplasmic, score: 7.50.
 0.990
KWZ75546.1
KEGG: gvh:HMPREF9231_0432 2.6e-130 acetyl-CoA C-acetyltransferase; K00626 acetyl-CoA C-acetyltransferase; Psort location: Cytoplasmic, score: 9.97; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.979
KWZ75985.1
Diphosphomevalonate decarboxylase; KEGG: sst:SSUST3_0299 4.1e-84 mvaD; mevalonate diphosphate decarboxylase; K01597 diphosphomevalonate decarboxylase.
 
 
 0.871
KWZ73407.1
Prenyltransferase, UbiA family; KEGG: gob:Gobs_4565 6.2e-26 1,4-dihydroxy-2-naphthoateoctaprenyltransferase; K02548 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 
 0.843
KWZ75986.1
KEGG: ssf:SSUA7_0272 3.1e-47 mevalonate kinase; K00938 phosphomevalonate kinase; Psort location: Cytoplasmic, score: 7.50.
 
 0.803
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.754
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.621
KWZ73553.1
Polyprenyl synthetase; KEGG: bde:BDP_1413 6.9e-66 idsA; polyprenyl synthase K13787; Psort location: Cytoplasmic, score: 9.97; Belongs to the FPP/GGPP synthase family.
  
 
 0.521
KWZ75547.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.442
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.