STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75347.1Hypothetical protein; KEGG: lsa:LSA1188 3.4e-29 pox1; pyruvate oxidase K00158. (83 aa)    
Predicted Functional Partners:
KWZ75348.1
Hypothetical protein; KEGG: lsa:LSA1188 7.3e-29 pox1; pyruvate oxidase K00158.
     0.991
KWZ75346.1
Hypothetical protein; KEGG: lsl:LSL_1372 3.7e-44 pyruvate oxidase K00158; Psort location: Cytoplasmic, score: 7.50.
     0.990
KWZ75349.1
Thiamine pyrophosphate enzyme, TPP binding domain protein; KEGG: lsa:LSA1188 3.1e-79 pox1; pyruvate oxidase K00158; Psort location: CytoplasmicMembrane, score: 8.78.
     0.990
KWZ73368.1
Acetolactate synthase, small subunit; Psort location: Cytoplasmic, score: 7.50.
  
 0.917
KWZ75216.1
KEGG: bad:BAD_0688 3.1e-173 pta; phosphate acetyltransferase; K13788 phosphate acetyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.737
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 
 0.685
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.644
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.633
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.614
KWZ72824.1
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate).
  
 
 0.612
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
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