node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ73602.1 | glmU | HMPREF3214_01059 | HMPREF3214_00631 | KEGG: bbf:BBB_0562 2.0e-123 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase K01928; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.932 |
KWZ73602.1 | murA | HMPREF3214_01059 | HMPREF3214_01406 | KEGG: bbf:BBB_0562 2.0e-123 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase K01928; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.789 |
KWZ73602.1 | murC | HMPREF3214_01059 | HMPREF3214_01023 | KEGG: bbf:BBB_0562 2.0e-123 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase K01928; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.975 |
KWZ73602.1 | murD | HMPREF3214_01059 | HMPREF3214_01020 | KEGG: bbf:BBB_0562 2.0e-123 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase K01928; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.998 |
KWZ74710.1 | glmU | HMPREF3214_00632 | HMPREF3214_00631 | HAD hydrolase family; KEGG: cmi:CMM_0484 1.3e-87 nagD; putative N-acetylglucosamine-6-phosphate deacetylase K02566; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.820 |
KWZ74710.1 | rsfS | HMPREF3214_00632 | HMPREF3214_00630 | HAD hydrolase family; KEGG: cmi:CMM_0484 1.3e-87 nagD; putative N-acetylglucosamine-6-phosphate deacetylase K02566; Psort location: Cytoplasmic, score: 7.50. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.726 |
KWZ74712.1 | glmM | HMPREF3214_00635 | HMPREF3214_00936 | KEGG: blk:BLNIAS_01811 2.6e-146 prsA2; ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase; Psort location: Cytoplasmic, score: 9.97. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.581 |
KWZ74712.1 | glmS | HMPREF3214_00635 | HMPREF3214_01617 | KEGG: blk:BLNIAS_01811 2.6e-146 prsA2; ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase; Psort location: Cytoplasmic, score: 9.97. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.500 |
KWZ74712.1 | glmU | HMPREF3214_00635 | HMPREF3214_00631 | KEGG: blk:BLNIAS_01811 2.6e-146 prsA2; ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.959 |
KWZ75216.1 | glmU | HMPREF3214_00528 | HMPREF3214_00631 | KEGG: bad:BAD_0688 3.1e-173 pta; phosphate acetyltransferase; K13788 phosphate acetyltransferase; Psort location: Cytoplasmic, score: 7.50. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.875 |
glmM | KWZ74712.1 | HMPREF3214_00936 | HMPREF3214_00635 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | KEGG: blk:BLNIAS_01811 2.6e-146 prsA2; ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase; Psort location: Cytoplasmic, score: 9.97. | 0.581 |
glmM | glmS | HMPREF3214_00936 | HMPREF3214_01617 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.993 |
glmM | glmU | HMPREF3214_00936 | HMPREF3214_00631 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.997 |
glmM | murA | HMPREF3214_00936 | HMPREF3214_01406 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.421 |
glmM | murC | HMPREF3214_00936 | HMPREF3214_01023 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.775 |
glmM | murD | HMPREF3214_00936 | HMPREF3214_01020 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.482 |
glmS | KWZ74712.1 | HMPREF3214_01617 | HMPREF3214_00635 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | KEGG: blk:BLNIAS_01811 2.6e-146 prsA2; ribose-phosphate pyrophosphokinase; K00948 ribose-phosphate pyrophosphokinase; Psort location: Cytoplasmic, score: 9.97. | 0.500 |
glmS | glmM | HMPREF3214_01617 | HMPREF3214_00936 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.993 |
glmS | glmU | HMPREF3214_01617 | HMPREF3214_00631 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.954 |
glmU | KWZ73602.1 | HMPREF3214_00631 | HMPREF3214_01059 | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | KEGG: bbf:BBB_0562 2.0e-123 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase K01928; Psort location: Cytoplasmic, score: 7.50. | 0.932 |