STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74716.1Threonine synthase; KEGG: blj:BLD_0786 6.5e-173 thrC; threonine synthase; K01733 threonine synthase; Psort location: Cytoplasmic, score: 7.50. (506 aa)    
Predicted Functional Partners:
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 0.999
KWZ72254.1
ACT domain protein; KEGG: blv:BalV_1534 4.0e-54 threonine dehydratase; K01754 threonine dehydratase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.972
KWZ75384.1
KEGG: bbi:BBIF_0263 1.4e-131 thrA; Homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
 
 0.961
serC
Putative phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
   
 0.957
KWZ73714.1
Beta-eliminating lyase; KEGG: lba:Lebu_2061 6.1e-90 threonine aldolase; K01620 threonine aldolase; Psort location: Cytoplasmic, score: 7.50.
   
 0.954
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
  
 0.730
KWZ72820.1
Amino acid kinase family protein; KEGG: bll:BLJ_0147 1.9e-104 aspartate kinase; K00928 aspartate kinase; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
  
 
 0.643
KWZ72821.1
ACT domain protein; KEGG: bbp:BBPR_1750 1.3e-55 askB; aspartokinase K00928; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.643
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.620
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.605
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.