Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KWZ73809.1Phospholipase D domain protein; KEGG: rho:RHOM_11560 2.9e-76 cardiolipin synthase; K06131 cardiolipin synthase; Psort location: CytoplasmicMembrane, score: 9.99. (319 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.737
KWZ73353.1
Endonuclease/exonuclease/phosphatase family protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
  0.573
KWZ73565.1
KEGG: bad:BAD_1028 8.2e-63 pgsA3; DP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
  
 0.567
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.508
KWZ72844.1
Methyltransferase domain protein; KEGG: bce:BC2100 1.3e-14 methyltransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.507
KWZ75897.1
PAP2 family protein; KEGG: reh:H16_A0767 2.6e-17 pgpB; membrane-associated phospholipid phosphatase; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.501
KWZ75654.1
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
    
 0.493
KWZ72660.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
    
  0.470
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
    
 0.469
KWZ73549.1
KEGG: apb:SAR116_1990 6.5e-09 major facilitator superfamily protein; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
  0.459
Your Current Organism:
Alloscardovia omnicolens
NCBI taxonomy Id: 419015
Other names: A. omnicolens, Alloscardovia omnicolens Huys et al. 2007, CCUG 31649, DSM 21503, LMG 23792, LMG:23792
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