node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ73476.1 | KWZ73480.1 | HMPREF3214_01248 | HMPREF3214_01252 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Preprotein translocase, YajC subunit. | 0.666 |
KWZ73476.1 | apt | HMPREF3214_01248 | HMPREF3214_01253 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.562 |
KWZ73476.1 | ruvA | HMPREF3214_01248 | HMPREF3214_01250 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.914 |
KWZ73476.1 | ruvB | HMPREF3214_01248 | HMPREF3214_01251 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.770 |
KWZ73476.1 | ruvC | HMPREF3214_01248 | HMPREF3214_01249 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.881 |
KWZ73480.1 | KWZ73476.1 | HMPREF3214_01252 | HMPREF3214_01248 | Preprotein translocase, YajC subunit. | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.666 |
KWZ73480.1 | apt | HMPREF3214_01252 | HMPREF3214_01253 | Preprotein translocase, YajC subunit. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.805 |
KWZ73480.1 | polA | HMPREF3214_01252 | HMPREF3214_00535 | Preprotein translocase, YajC subunit. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.441 |
KWZ73480.1 | ruvA | HMPREF3214_01252 | HMPREF3214_01250 | Preprotein translocase, YajC subunit. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.737 |
KWZ73480.1 | ruvB | HMPREF3214_01252 | HMPREF3214_01251 | Preprotein translocase, YajC subunit. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.755 |
KWZ73480.1 | ruvC | HMPREF3214_01252 | HMPREF3214_01249 | Preprotein translocase, YajC subunit. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.644 |
KWZ74718.1 | polA | HMPREF3214_00641 | HMPREF3214_00535 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.466 |
KWZ74718.1 | recA | HMPREF3214_00641 | HMPREF3214_01335 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.877 |
KWZ74718.1 | recO | HMPREF3214_00641 | HMPREF3214_00984 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.718 |
KWZ74718.1 | recR | HMPREF3214_00641 | HMPREF3214_01535 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.506 |
KWZ74718.1 | ruvA | HMPREF3214_00641 | HMPREF3214_01250 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.658 |
KWZ74718.1 | ruvB | HMPREF3214_00641 | HMPREF3214_01251 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.623 |
KWZ74718.1 | ruvC | HMPREF3214_00641 | HMPREF3214_01249 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.424 |
apt | KWZ73476.1 | HMPREF3214_01253 | HMPREF3214_01248 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 9.8e-67 glucose-1-phosphate adenylyltransferase; Psort location: Cytoplasmic, score: 7.50. | 0.562 |
apt | KWZ73480.1 | HMPREF3214_01253 | HMPREF3214_01252 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Preprotein translocase, YajC subunit. | 0.805 |